Evaluation of effectiveness of a lab test in detecting diseases of middle layer of eye
Not Applicable
- Conditions
- Health Condition 1: H200- Acute and subacute iridocyclitis
- Registration Number
- CTRI/2021/02/031276
- Lead Sponsor
- Aravind Eye Hospital Pondicherry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients attending the uvea clinic who are newly diagnosed with acute uveitis who are willing to undergo the test at the reference laboratory attached to Aravind Eye hospital, Pondicherry
Chronic uveitis patients presenting with reactivation of the disease
Patients of age 18 years and above
Exclusion Criteria
Patients with history of trauma
Chronic uveitis patients with inactive disease
Patients in the pediatric age groups
Immunosuppressed patients
Patients who are already on ACE inhibitors oral steroids or immunosuppressants
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of raised S.ACE levels (52IU/L) among patients with active uveitis <br/ ><br> <br/ ><br>Estimated values of Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value of serum ACE investigation in different etiologies of uveitis including ocular TB and Ocular Sarcoidosis by employing different cut-off values <br/ ><br>Timepoint: At 1 year
- Secondary Outcome Measures
Name Time Method Percentage of positive Mantoux test value of more than 10mm and estimated values of Sensitivity, Specificity, Positive Predictive value and Negative Predictive Value of Mantoux test in Ocular TB and Ocular Sarcoidosis <br/ ><br> <br/ ><br>Percentage of occurrence of lymphopenia and estimated values of Sensitivity, Specificity, Positive Predictive value and Negative Predictive value of lymphopenia in Ocular TB and Ocular Sarcoidosis <br/ ><br>Timepoint: At Baseline (Day 0)