Feasibility study of the adjuvant chemoradiotherapy for the patients with high-risk rectal submucosal invasive cancer after the local resectio
- Conditions
- rectal cancer
- Registration Number
- JPRN-UMIN000016785
- Lead Sponsor
- ational Cancer Center Hospital East
- Brief Summary
One patient was ineligible. Twenty-three patients completed treatment, with a completion rate of 82% (80% confidence interval, 69-91%); the remaining five patients completed treatment with protocol deviation. The median relative dose intensity of capecitabine was 100% (range, 58-100%). Common adverse events included radiation dermatitis (54%), anal pain (39%) and anal mucositis (29%). No grade-3 or higher adverse events were reported.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 29
Not provided
1)Presence of synchronous or metachronous advanced colorectal cancer and malignant diseases in any other organs 2)Pregnant woman 3)Patients with psychosis 4)Use of the phenytoin and warfarin potassium 5)Use of steroids 6)Activity of hepatitis B or hepatitis C 7)Systemic infection 8)Others
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of treatment completion
- Secondary Outcome Measures
Name Time Method