Early awake prone positioning combined with non-invasive oxygen therapy in patients with COVID-19
- Conditions
- COVID-19, acute hypoxemic respiratory failure
- Registration Number
- JPRN-UMIN000045889
- Lead Sponsor
- Mexican Secretariat of Health Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran. Intensive Care Unit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 384
Not provided
1.Patients in palliative care 2.Patients with imminent orotracheal intubation according to refractory hypoxemia with acute respiratory distress syndrome (ARDS), acute respiratory acidosis (pH < 7.15, PaCO2 >45 mmHg) with ARDS, requirement of airway protection. 3.Patients with unsolved shock (reanimation phase or norepinephrine dose greater than or equal to 0.15 mcg/kg/min). 4.Unstable arrythmias (bradycardia o tachycardia). 5.Mental agitation or altered mental state (Glasgow Comma Scale <10 points) that would impede cooperation to self-prone. 6.Instability of the pelvis, vertebral column, or femur due to recent surgery or trauma. 7.Anatomical alterations that limit the adoption of prone position (severe kyphoscoliosis, muscle contracture, or other). 8.Abdominal surgery in the last 15 days. 9.Thoracic lesion or surgery in the last 15 days. 10.Pregnancy 11.Intracranial hypertension 12.Deep vein thrombosis in the last 2 days. 13.Heart pacemaker surgery in the last 2 days. 14.Chest tube with air leak 15.Recent facial trauma or surgery 16.Morbid obesity (BMI >40 kg/m2) 17.Pressure lesions or ulcers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method