The development of new diagnostic tools in food allergy
Withdrawn
- Conditions
- food hypersensitivityfood allergy10001708
- Registration Number
- NL-OMON34148
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adults (from 18 years) with a (suspicion of) legume (peanut, soy), nut (hazel nut, pecan nut, cashew nut, walnut), cow's milk, fish, egg, shrimp or latex allergy
Exclusion Criteria
congenital/acquired immunodeficiency
lymphoproliferative disease
systemic immunosuppression
Only when patients will undergo a food challenge:
instabile asthma
contra-indication for treatment with epinephrine (instabile angina pectoris, poor controlled hypertension or arrhythmia)
use of β-blocker or ACE inhibitor
pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To develop a model to predict (the severity of) a food allergy. </p><br>
- Secondary Outcome Measures
Name Time Method <p>-New biomarker(s) that can predict (the severity of) a food allergy<br /><br>-To compare sensitivity, specificity and positive and negative predictive value<br /><br>for different diagnostic tests: allergen chip, CAP, skin prick tests, basophil<br /><br>activation test (BAT) and T cell activity<br /><br>-Eliciting doses in walnut allergic patients </p><br>