Design and evaluation of multichannel stimulation algorithms to support hand opening during functional reach-to-grasp movements in stroke patients

Completed

Conditions: CVA
stroke
10007963

Registration Number: NL-OMON38359

Lead Sponsor: Roessingh Research & Development

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

Inclusion criteria for stroke patients are:
1. a history of a single unilateral stroke in the medial cerebral artery (MCA) region resulting in single-sided hemiparesis.
2. the onset of the stroke was more than six weeks ago
3. the ability to voluntarily generate 20 degrees excursions in the plane of elevation (horizontal ab-/adduction) and elevation angle (ab-/adduction, ante-/retroflexion) of the shoulder joint.
4. the ability to voluntarily generate an excursion of 20 degrees of elbow flexion/extension,
5. the ability to voluntarily extend the wrist 10 degrees from neutral flexion/extension
6. adequate cognitive function to understand the experiments, follow instructions, and give feedback to the researchers.;Inclusion criteria for healthy elderly are:
1. ability to decide whether or not to participate in the experiment and sign an informed consent.

Exclusion Criteria

Exclusion criteria for both stroke patients and healthy elderly are:
1. a fixed contracture deformity in the affected upper limb was present
2. pain as a limiting factor for the subject's active range of motion
3. age below 40 years

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter of the present experiment is the Box and Block test<br /><br>which measures hand function of stroke patients. This functional measure is<br /><br>used to evaluate the influence of different types of electrical stimulation on<br /><br>functional hand opening. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are muscle activation patterns (MAP) measured with<br /><br>electromyography and kinematics during reach-to-grasp movements. </p><br>