ORegon CHild Absenteeism Due to Respiratory Disease Study - Air Surveillance
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 422
- 试验地点
- 1
- 主要终点
- Rate of virus detection
研究概览
简要总结
The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air.
Participants will provide nasal swabs and have an air sample surveillance device installed in their home.
详细描述
The purpose of ORCHARDS-AIR is to utilize air surveillance in participant homes in conjunction with individually collected nasal specimens to assess their concordance and evaluate the significance of airborne detection with household transmission of common respiratory pathogens such as influenza and SARS-CoV-2.
The researchers postulate that households with documented and probable respiratory pathogen transmission will have higher rates of in-home air surveillance detection. Students with more severe illnesses will be absent more often and spend more time at home, potentially leading to absenteeism being associated with greater air surveillance detections and intrahousehold transmission.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 4 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Students:
- •Student attends, or is eligible to attend, a school within the Oregon School District (OSD)
- •Study has an illness characterized by at least 2 of 6 acute respiratory infection (ARI)/ILI symptoms (nasal discharge, nasal congestion, sneezing, sore throat, cough, fever) and student scores at least 2 points on the Jackson scale
排除标准
- •Students:
- •Household member listed on Wisconsin Department of Corrections Sex Offender Registry
- •Illness onset more than 7 days before anticipated time of specimen collection
- •Anatomical defect for which nasal specimen collection is contraindicated
- •Student participated too recently (<7 days from day 14 during peak influenza / COVID-19 period and <30 days during other times, as determined by a medically-attended surveillance program)
- •Inclusion Criteria - Household member:
- •Live in the same household as eligible student participant
- •Any age and gender
- •Fluent in English
- •Able to provide appropriate consent or assent
研究组 & 干预措施
Students with ARI (acute respiratoy infection)
Students with ARI and their household members will provide nasal swabs
干预措施: Indoor air quality monitor (Device)
Students with ARI (acute respiratoy infection)
Students with ARI and their household members will provide nasal swabs
干预措施: Nasal swab (Diagnostic Test)
结局指标
主要结局
Rate of virus detection
时间窗: Day 0, Day 7, Day 14
Participants will provide nasal swabs, which will be tested for a panel of viruses.
Rate of air sampling detection among families with documented transmission
时间窗: Day 7, Day 14
Study team will collect and test air sampler filter for viruses.
Rate of air sampling detection among families without documented transmission
时间窗: Day 7, Day 14
Study team will collect and test air sampler filter for viruses.
Survey of symptoms - day 7
时间窗: Day 7
Qualitative survey of participants' symptoms and related activities.
Survey of symptoms - day 14
时间窗: Day 14
Qualitative survey of participants' symptoms and related activities.
Air sampler use survey
时间窗: Day 7, Day 14
Qualitative survey about participants' use of the air sampler.
Rate of virus detection
时间窗: Day 0, Day 7, Day 14
Participants will provide nasal swabs, which will be tested for a panel of viruses.
Rate of air sampling detection among families with documented transmission
时间窗: Day 7, Day 14
Study team will collect and test air sampler filter for viruses.
Survey of symptoms - day 7
时间窗: Day 7
Qualitative survey of participants' symptoms and related activities.
Survey of symptoms - day 14
时间窗: Day 14
Qualitative survey of participants' symptoms and related activities.
Air sampler use survey
时间窗: Day 7, Day 14
Qualitative survey about participants' use of the air sampler.
Rate of air sampling detection among families without documented transmission
时间窗: Day 7, Day 14
Study team will collect and test air sampler filter for viruses.
Survey of symptoms - day 0
时间窗: Day 0
Qualitative survey of participants' symptoms and related activities.
次要结局
- Number of absences(14 days)
- Number of absences(14 days)