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Clinical Trials/ISRCTN72151906
ISRCTN72151906
Completed
Not Applicable

Randomised controlled trial of post-operative goal-directed haemodynamic therapy following a cardiac surgery and the effects on acute kidney injury

St George's Healthcare NHS Trust (UK)0 sites4,000 target enrollmentNovember 25, 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Complications following cardiac surgery, specifically acute kidney injury and renal function
Sponsor
St George's Healthcare NHS Trust (UK)
Enrollment
4000
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
November 25, 2013
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
St George's Healthcare NHS Trust (UK)

Eligibility Criteria

Inclusion Criteria

  • 1\. Coronary artery bypass grafts (CABG), aortic valve replacement (AVR) or combined CABG and AVR
  • 2\. Informed consent
  • 3\. Admission to intensive care from theatre
  • 4\. Patients over 18 years of age

Exclusion Criteria

  • 1\. Myocardial infarction (MI) less than 48 hours prior to surgery
  • 2\. Infective endocarditis
  • 3\. Chronic Kidney Disease Stage 5 (end stage renal failure)
  • 4\. Cardiogenic shock requiring intra\-aortic balloon pump
  • 5\. Pulmonary hypertension WHO\-FC III/IV
  • 6\. Known right ventricular failure
  • 7\. Diagnosis of congenital heart disease
  • Added 14/10/2014:
  • 8\. Renal replacement therapy prior to surgery within 30 days

Outcomes

Primary Outcomes

Not specified

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