Study comparing conduction in median nerve after treatment with Gabapentin or Amitriptyline in Diabetic patients suffering from neuropathic pain,and also comparing effectiveness and safety of both drugs
Not Applicable
- Conditions
- Health Condition 1: null- Daibetes mellitus with peripheral neuropathic pain
- Registration Number
- CTRI/2018/05/013750
- Lead Sponsor
- Government Medical College Patiala
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with established diagnosis of type 2 Daibetes mellitus, clinically relevant Diabetic peripheral neuropathic pain, Patients willing to sign informed consent form
Exclusion Criteria
Patients already on treatment of neuropathy of different cause, presence of renal, hepatic or cardiovascular insufficiency, patients with epilepsy, uncontrolled hypertension and substance abuse, current/previous diagnosis of psychiatric disorder, pregnant and lactating females, patients taking such drugs for any other disease which are known to cause drug interactions with amitriptyline or gabapentin, patients taking drugs which can cause neuropathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare the effect of Gabapentin and Amitriptyline on improvement of nerve conduction in subjects of type 2 DM with peripheral neuropathic pain- Nerve conduction studyTimepoint: 4 months
- Secondary Outcome Measures
Name Time Method To study and compare the efficacy and safety of Gabapentin vs Amitriptyline- Michigan neuropathy screening instrument, visual analog scale and adverse drug reactionsTimepoint: 4 months