Role of less affected upper extremity in post stroke rehabilitation
试验速览
- 阶段
- 3 期
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Fugl-Meyer assessment, Purdue peg board test, Minnesota rate of manipulation test (MRMT)
研究概览
简要总结
Background: The damage of some fibers of the corticospinal tract may lead tomild to moderate impairment on sound side also. The sound side (the"unaffected"side) is often considered a reference point.It is thereforeassumed that this side has no deficit. Nevertheless,previousresearch suggests or tends to show diminished strength intheunaffected upper limb whencomparedwithhealthy subjects. However, the rehabilitation protocols emphasized only on theaffected side. In spite of this majority of the stroke population do not achievecomplete or satisfactory motor recovery of the affected side. Animal studies have shown that the retrainingof the less affected side also, leads to better cortical reorganization whichin turn add up to improved motorrecovery of the affected upper limb.
Objectives
· Tostudy the level of impairment in less affected upper extremity of strokepatients
· Tocompare the preference between dominantand non-dominant less affected hand
· Todevelop Occupational therapy intervention protocol focused on intralimb(bilateral upper limb) coordination and exclusive strengthening & dexteritytraining of the less affected side
· Tostudy the effect of the protocol in comparison to the conventional program
Methodology
StudyDesign: Part- I Comparison of less affected upper limb of post stroke patients withmatched able body individuals (Non-experimental: observational). Part-IIComparison of the new treatment protocol with the conventional (experimental;randomized controlled trial)Place of study: Department of Occupational Therapy, PDUIPH
Inclusioncriteria**:** Age: 40 to 60 year, bothmale & female**,** Hemiparesis(right / left), unilateral stroke(Ischemic / hemmorhagic), 4 to 12 months after stroke
Exclusioncriteria**:** Receptive communicationdisorder**,** Cerebellar or thalamicinfarct**,** Uncontrolledsystemic or cardiovascular disease**,multiple stroke,** Ataxia**,** Severecognitive / perceptual deficit
Samplesize: 30 post strokepatients (Pilot study) and 30 matched able body individuals (Allthe participants will be enrolled after obtaining signed informed consent form)
SamplingMethod: Sample of convenience, Random assignment
Outcomemeasures: Purdue peg board test, Minnesota rate ofmanipulation test (MRMT) (Both themeasures are already available in the Department of Occupational therapy,PDUIPH
Deliverableoutcomes
· Thepresent study will lead to development of rehabilitation protocol whichencompasses less affected side also.
· Assessmentand training of less affected upper extremity will enhance better motor andfunctional outcome in post stroke survivors.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •40 to 60 year, both male & female, Hemiparesis (right / left), unilateral stroke (Ischemic / hemmorhagic), 4 to 12 months after stroke.
排除标准
- •Receptive communication disorder, Cerebellar or thalamic infarct, Uncontrolled systemic or cardiovascular disease, multiple stroke, Ataxia, Severe cognitive / perceptual deficit.
结局指标
主要结局
Fugl-Meyer assessment, Purdue peg board test, Minnesota rate of manipulation test (MRMT)
时间窗: pre, at 6th week post intervention
次要结局
- brunnstrom recovery stage, MMT grades(pre, at 6th week post intervention)
