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Clinical Trials/NCT00658502
NCT00658502
Unknown
Not Applicable

Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment

Far Eastern Memorial Hospital1 site in 1 country100 target enrollmentMarch 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myopia
Sponsor
Far Eastern Memorial Hospital
Enrollment
100
Locations
1
Primary Endpoint
axial length, corneal hysteresis
Last Updated
18 years ago

Overview

Brief Summary

Our study has three parts has three parts, and the main aim of the study is to find out if corneal hysteresis was associated with myopia or even a predictor of myopia poor control predictor:

  • Part 1 of our study: patients with anisomeropia whose spherical equivalent refraction as measured by cycloplegic autorefraction between the two eyes differ greater than 1.5 D.
  • Part 2 of our study: Minus spherical equivalent refraction as measured by cycloplegic autorefraction.
  • Part 3 of our study: patients with minus spherical equivalent refraction as measured by cycloplegic autorefraction who are under regular atropine for the treatment of myopia;patients who are prescribed with atropine treatment are in need of myopia control instead of for research interest
Registry
clinicaltrials.gov
Start Date
March 2008
End Date
August 2009
Last Updated
18 years ago
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Normal ocular health other than myopia or anisometropia
  • In good general health with no history of prematurity or cardiac or significant respiratory diseases
  • No allergy to atropine, tropicamide, proparacaine, and benzalkonium chloride
  • No previous or current use of contact lenses, bifocals, progressive addition lenses
  • No amblyopia or manifest strabismus, including intermittent tropia

Exclusion Criteria

  • presence of keratoconus or other corneal disease
  • previous eye drops usage except Atropine
  • major ocular surgery history (including refractive surgery, scleral buckle, glaucoma filtering, cornea transplant, cataract and vitreoretinal surgery)
  • presence of other ocular conditions such as glaucoma, uveitis, or other ocular inflammatory or vitreoretinal diseases.

Outcomes

Primary Outcomes

axial length, corneal hysteresis

Time Frame: 3 month

Secondary Outcomes

  • Refractive error, visual acuity, , intraocular pressure, , and corneal thickness(3 month)

Study Sites (1)

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