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THE IMPACT OF HIGH VERSUS STANDARD ENTERAL PROTEIN PROVISION ON FUNCTIONAL RECOVERY FOLLOWING INTENSIVE CARE ADMISSION: A RANDOMIZED CONTROLLED, MULTICENTER, PARALLEL GROUP TRIAL IN MECHANICALLY VENTILATED, CRITICALLY ILL PATIENTS

Recruiting
Conditions
Critical illness (aandoening die IC opname nodig maakt)
Critical illness
IC admission
Registration Number
NL-OMON52851
Lead Sponsor
Medisch Universitair Ziekenhuis Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
515
Inclusion Criteria

* Adult (>= 18 years) patient admitted to the ICU
* Unplanned ICU admission
* Invasive mechanical ventilation initiated <24 hours following ICU admission
* Expected ICU stay on mechanical ventilation of >= 3 days

Exclusion Criteria

* Contraindication for enteral nutrition at the discretion of the treating
physician
* Moribund or expected withholding of treatment
* Kidney failure and *no dialysis*-code on admission
* Hepatic encephalopathy (West Haven criteria 3-4)
* Body mass index <18 kg/m²

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Overall between group-differences in health Related Quality of Life (HRQL) at<br /><br>30 days, 90 days and 180 days after index ICU admission, assessed by EuroQoL<br /><br>(EQ-5D-5L).</p><br>
Secondary Outcome Measures
NameTimeMethod
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