The effect of lactulose on administration on nitrogen waste products
Early Phase 1
- Conditions
- Condition 1: Chrontic Renal Failure stages 3. Condition 2: Chronic Renal Failure (stage 4).Moderate Chronic Renal Failure (stage 3)Severe Chronic Renal Failure (stage 4)
- Registration Number
- IRCT201105316666N1
- Lead Sponsor
- Tabriz University Of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion criteria :1)The patients with stages 3 and 4 of CRF 2The patients who are older than 18 years of age3) The patients who have consent to continue the study. Exclusion criteria:1) History of any probiotic, sinbiotic and antibiotic use during one month prior to the study2) patients with intolerance to lactolose or patients how create complications.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method P-cresyl sulfate. Timepoint: at the end of the study and 1 month after the study. Method of measurement: at the end of the study and 1 month after the study.;Indoxyl sulfate. Timepoint: at the end of the study and 1 month after the study. Method of measurement: High Performance Liquid Chromatography = HPLC.;Advanaced Glycation End (AGE) Products. Timepoint: at the end of the study and 1 month after the study. Method of measurement: High Performance Liquid Chromatography = HPLC.
- Secondary Outcome Measures
Name Time Method C-Reactive Protein = CRP. Timepoint: at the end of the study and after 1 month. Method of measurement: Standard lab test.