NCT02380833已完成不适用
The Effectiveness of a Paleolithic Based Diet Compared to MyPlate Guidelines, With and Without Exercise, on Physical Conditioning in Women: a Randomized Controlled Trial.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Change in anaerobic power
研究概览
简要总结
The purpose of this study is to determine the effectiveness of recommending either a Paleolithic based diet or the United States Department of Agriculture MyPlate guidelines with or without exercise on physical conditioning, hormones related to energy metabolism, body composition, resting energy expenditure, blood biomarkers, and urine in young, adult females.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •body fat percent between 20 and 38
- •less than 150 minutes of exercise per week at 4.5 or greater Metabolic Equivalent of Task
- •not pregnant, trying to become pregnant or lactating
- •non-smoker
- •no previous resistance training
- •have not been on a diet in the past three months
- •no dietary restrictions (food allergies, disease conditions, etc)
- •have not lost more than 10 lbs. in the past three months
排除标准
- •taking any medication
- •women who have had a left breast mastectomy
- •do not meet criteria of PAR-Q
结局指标
主要结局
Change in anaerobic power
时间窗: Baseline and 8 weeks
Wingate anaerobic threshold
Change in aerobic conditioning
时间窗: Baseline and 8 weeks
Peak oxygen consumption
Change in strength
时间窗: Baseline and 8 weeks
Chest press and leg press estimated one repetition maximum
次要结局
- Change in tumor necrosis factor alpha (plasma)(Baseline and 8 weeks)
- Change in interleukin 6 (plasma)(Baseline and 8 weeks)
- Change in undercarboxylated osteocalcin (plasma)(Baseline and 8 weeks)
- Change in total cholesterol (plasma)(Baseline and 8 weeks)
- Change in urine(Baseline and 8 weeks)
- Change in glucagon (plasma)(Baseline and 8 weeks)
- Change in leptin (plasma)(Baseline and 8 weeks)
- Change in resting energy expenditure(Baseline and 8 weeks)
- Change in insulin (plasma)(Baseline and 8 weeks)
- Change in ghrelin (plasma)(Baseline and 8 weeks)
- Change in non-esterified fatty acids (plasma)(Baseline and weeks)
- Change in ketones (plasma)(Baseline and 8 weeks)
- Change in peptide YY 3-36 (plasma)(Baseline and 8 weeks)
- Change in adiponectin (plasma)(Baseline and 8 weeks)
- Change in non-HDL cholesterol (plasma)(Baseline and 8 weeks)
- Change in HDL cholesterol (plasma)(Baseline and 8 weeks)
- Change in glucose (plasma)(Baseline and 8 weeks)
- Change in fat mass(Baseline and 8 weeks)
- Change in bone mass(Baseline and 8 weeks)
- Change in triacylglycerol (plasma)(Baseline and 8 weeks)
- Change in fat free mass(Baseline and 8 weeks)
研究者
Elliot D. Jesch
Assistant Professor
Clemson University
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Effects of an intervention with a Paleolithic diet in subjects with the metabolic syndrome (MetS). A pilot-study.Metabolic Syndome, Metabool syndroom, Cardiovascular risk, Cardiovasculair risicoNL-OMON22601ouis Bolk Institute, DriebergenWUR, WageningenUMCG, GroningenUniversity of Gerona, Spain36
已完成
不适用
Effects of a Paleolithic Lifestyle Intervention in Breast Cancer Patients Undergoing RadiotherapyBody Weight ChangesBreast CancerNCT04574323MVZ Leopoldina GmbH13
已完成
不适用
Paleolithic Diet and Exercise StudyDietNCT00360516University of California, San Francisco10
已完成
2 期
Paleolithic Diet in the Treatment of Glucose IntoleranceCoronary Heart DiseaseHyperglycemiaNCT00419497Lund University Hospital29
已完成
不适用
Paleolithic Diets vs T2D and Improvements in the Metabolic SyndromeType 2 Diabetes MellitusNCT00548782University of California, San Francisco22