Transplantation of a scaffold-free tissue engineered construct (TEC) derived from autologous synovial mesenchymal stem cells for cartilage repair - Transplantation of a scaffold-free tissue engineered construct (TEC) for cartilage repair

Department of Orthopaedics, Osaka University Graduate School of Medicine0 个研究点目标入组 5 人开始时间: 2012年7月1日最近更新: 2023年10月17日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方
入组人数: 5

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

o adverse events were recorded, and self-assessed clinical scores for pain, symptoms, activities of daily living, sports activity, and quality of life were significantly improved at 24 months after surgery. Secure defect filling was confirmed by second-look arthroscopy and magnetic resonance imaging in all cases. Histology of biopsy specimens indicated repair tissue approaching the composition and structure of hyaline cartilage.

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 60years-old（—）
性别: All

入选标准

未提供

排除标准

•Patients with 1) Active local infection 2) Serious complications including malignancies 3) Alchol or drung abuse 4) Rheumatoid arthritis, gout, or pseudo gout 5) Abnormal alignment of lower extremity 6) Patello-femoral instability 7) Diabetes 8) Renal failure which requires dialysis 9) Infectious disease (HIV, HBV, HCV, HTLV, syphilis) 10) Pregnancy 11) the medication of corticosteroids 12) participation in other clinical trials 13)Judged inappropriate with other reason by the project investigators.

研究者

发起方

Department of Orthopaedics, Osaka University Graduate School of Medicine

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