Intra-abdominal Hypertension in Critically Ill Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 286
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.
详细描述
Increased pressure within the abdominal cavity is particularly common in intensive care patients and has been shown to be an independent risk-factor for mortality in this patient population. The quoted rates of intra-abdominal hypertension of range anywhere from 20-60% are dependent on the population of patient studied. The prospective observational studies performed to date have been underpowered, used strict inclusion/exclusion criteria or were performed prior to consensus guidelines on the definition and measurement of intra-abdominal pressure and hypertension.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Foley catheter in-situ on admission
排除标准
- •Contra-indication to bladder pressure measurement
- •Home service asked that patient is not included
- •Death within 24 priors of admission before bladder pressure measured
- •No bladder pressure performed within 24 hours of admission
- •Consent refused or unable to be obtained (lack of SDM, patient unable to provide)
结局指标
主要结局
Mortality
时间窗: While patient in-hospital, expected stay one week on average
As measured prospectively by patient death in the ICU
次要结局
- Length of stay(While patient in-hospital, expected stay one week on average)
- Abdominal decompression(While patient in-hospital, expected stay one week on average)
研究者
Patrick Murphy
Resident
Western University, Canada