The Effect of Active Nutritional Support On The Incidence Of Mucositis And Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- nutritional status of patients
研究概览
简要总结
note effect of appropriate nutrition on head and neck cancer patients receiving radiotherapy
详细描述
Head and neck cancer (HNC) is the sixth most common cancer worldwide with more than half a million new cases diagnosed each year . Because of the limitations imposed by the complicated anatomical structure of the head and neck to the operation, radiotherapy (RT) has become the main treatment method for HNC. However, damage to the normal tissue surrounding the tumor is inevitable. The most common manifestations of injury caused by RT are mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20-30% of patients. Radiation-induced oral mucositis (RIOM) is a common side effect after radiotherapy (RT) in head and neck cancer (HNC) patients. RIOM patients with severe pain have difficulty in eating, which increases the incidence of malnutrition and affects patients' quality of life and the process of RT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •head and neck cancer patients with age >18
- •Newly diagnosed head and neck cancer patients
- •histological proven HNC cancer
- •head and neck cancer patients treated with radiotherapy or chemo radiotherapy
排除标准
- •Advanced and Metastatic head and neck cancer patients
- •head and neck cancer patients treated with chemotherapy only
结局指标
主要结局
nutritional status of patients
时间窗: two years
Follow up improvement by evaluating weight in kg and height in meters to calculate body mass index in kg / m\^2
次要结局
未报告次要终点
研究者
Reham Mohamed Aboelela Hassan
resident doctor at oncology department of Assiut university hospital
Assiut University
