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临床试验/NCT06477341
NCT06477341已完成不适用

The Effect of Active Nutritional Support On The Incidence Of Mucositis And Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

Assiut University1 个研究点 分布在 1 个国家目标入组 47 人开始时间: 2023年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
47
试验地点
1
主要终点
nutritional status of patients

研究概览

简要总结

note effect of appropriate nutrition on head and neck cancer patients receiving radiotherapy

详细描述

Head and neck cancer (HNC) is the sixth most common cancer worldwide with more than half a million new cases diagnosed each year . Because of the limitations imposed by the complicated anatomical structure of the head and neck to the operation, radiotherapy (RT) has become the main treatment method for HNC. However, damage to the normal tissue surrounding the tumor is inevitable. The most common manifestations of injury caused by RT are mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20-30% of patients. Radiation-induced oral mucositis (RIOM) is a common side effect after radiotherapy (RT) in head and neck cancer (HNC) patients. RIOM patients with severe pain have difficulty in eating, which increases the incidence of malnutrition and affects patients' quality of life and the process of RT.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • head and neck cancer patients with age >18
  • Newly diagnosed head and neck cancer patients
  • histological proven HNC cancer
  • head and neck cancer patients treated with radiotherapy or chemo radiotherapy

排除标准

  • Advanced and Metastatic head and neck cancer patients
  • head and neck cancer patients treated with chemotherapy only

结局指标

主要结局

nutritional status of patients

时间窗: two years

Follow up improvement by evaluating weight in kg and height in meters to calculate body mass index in kg / m\^2

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Reham Mohamed Aboelela Hassan

resident doctor at oncology department of Assiut university hospital

Assiut University

研究点 (1)

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