The Effect of Active Nutritional Support On Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

Not Applicable

Recruiting

• Conditions: Head and Neck Neoplasms
• Interventions: Dietary Supplement: various available nutrition as those contain high protein content as ensure milk

• Registration Number: NCT06477341
• Lead Sponsor: Assiut University

Brief Summary

note effect of appropriate nutrition on head and neck cancer patients receiving radiotherapy

Detailed Description

Head and neck cancer (HNC) is the sixth most common cancer worldwide with more than half a million new cases diagnosed each year . Because of the limitations imposed by the complicated anatomical structure of the head and neck to the operation, radiotherapy (RT) has become the main treatment method for HNC. However, damage to the normal tissue surrounding the tumor is inevitable. The most common manifestations of injury caused by RT are mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20-30% of patients. Radiation-induced oral mucositis (RIOM) is a common side effect after radiotherapy (RT) in head and neck cancer (HNC) patients. RIOM patients with severe pain have difficulty in eating, which increases the incidence of malnutrition and affects patients' quality of life and the process of RT.

Study Timeline

• Study Start: 2023-01-01
• Study First Submitted: 2024-03-26
• Status Verified: 2024-06
• Study First Submitted QC: 2024-06-21
• Last Update Submitted: 2024-06-21
• Study First Posted: 2024-06-27
• Last Update Posted: 2024-06-27
• Primary Completion: 2026-01-30
• Study Completion: 2026-03-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

• head and neck cancer patients with age >18
• Newly diagnosed head and neck cancer patients
• histological proven HNC cancer
• head and neck cancer patients treated with radiotherapy or chemo radiotherapy

Exclusion Criteria

• Advanced and Metastatic head and neck cancer patients
• head and neck cancer patients treated with chemotherapy only

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
nutritional support grouped	various available nutrition as those contain high protein content as ensure milk	patients of head and neck cancer receiving radiotherapy , who receive any nutritional support during radiotherapy whether oral or intravenous like dipeptivine for mucositis

Primary Outcome Measures

Name	Time	Method
nutritional status of patients	two years	Follow up improvement by evaluating weight in kg and height in meters to calculate body mass index in kg / m\^2

Trial Locations

Locations (1)

Reham mohamed; 🇪🇬 Assiut, Egypt