Comparison Of the effects of dexmedetomidine and remifentanil on intraoperative hemodynamics and postoperative pain in patients with spine surgery

Phase 3

• Conditions: S23.3XXD; Spine surgery.; Sprain of ligaments of thoracic spine, subsequent encounter

• Registration Number: IRCT20190618043934N27
• Lead Sponsor: Birjand University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

Age between 18 and 65 years
ASA class I or II
candidate for spine surgery
Having informed consent to participate in the study

Exclusion Criteria

Performing emergency surgery
History of previous spine surgery
Drug addiction
History of neuromuscular, psychiatric, pulmonary, cardiovascular diseases, orthostatic hypotension
Any type of brain pathology
Previous symptoms of ischemia or stroke
Carotid artery and spinal canal stenosis
Pregnant women
Allergic to the drugs used
Lack of control of systemic disease such as high blood pressure, diabetes and significant organ dysfunction of the heart
Unpredictable events occurred during the operation such as severe bleeding and surgery lasting more than 3 hours

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: The pain level is evaluated immediately after transfer to the ward, 2, 4, 6 and 8 hours after surgery by the study manager. Method of measurement: Using of Visual Analogue Scale.;Blood pressure: after induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.;Heart Rate: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.