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Clinical Trials/NCT04136041
NCT04136041
Completed
N/A

Study Protocol for a Pilot Randomized Controlled Trial on a Smartphone Application-based Intervention for Subthreshold Depression

Kibi International University1 site in 1 country32 target enrollmentOctober 29, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Subthreshold Depression
Sponsor
Kibi International University
Enrollment
32
Locations
1
Primary Endpoint
Depression severity as measured by the Center for Epidemiologic Studies Depression Scale (CES-D) score.
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The investigators plan to conduct a randomized controlled trial to examine whether a Smartphone-based Intervention improves subthreshold depression symptoms compared to no intervention.

The purpose of this pilot randomized controlled trial is to investigate the feasibility of the final randomized controlled trial.

Registry
clinicaltrials.gov
Start Date
October 29, 2019
End Date
March 5, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kazuki Hirao, PhD, OT

Assistant Professor

Kibi International University

Eligibility Criteria

Inclusion Criteria

  • 18 Years and older
  • Males and females
  • Center for Epidemiologic Studies Depression Scale score ≥16
  • Written informed consent prior to participation
  • Owns a smartphone with the iOS® operating system

Exclusion Criteria

  • Lifetime history of psychiatric disorders
  • Currently receiving treatment for a mental health problem from a mental health professional
  • Experience of a major depressive episode in the 2 weeks prior to the study, as ascertained using the Mini-International Neuropsychiatric Interview
  • Vision or hearing deficits that negatively impact everyday life

Outcomes

Primary Outcomes

Depression severity as measured by the Center for Epidemiologic Studies Depression Scale (CES-D) score.

Time Frame: Change from Baseline CES-D at 5 weeks

The CES-D is a 20-item self-report questionnaire used to measure depressive symptoms. The CES-D is a four-point Likert scale, with each item scored from 0 to 3. The total score ranges from 0 to 60 points. The higher the score, the stronger the depressive symptoms.

Secondary Outcomes

  • Psychological distress as measured by the Kessler Screening Scale for Psychological Distress (K6) score.(Change from Baseline K6 at 5 weeks)
  • Anxiety as measured by the 7-item Generalized Anxiety Disorder Scale (GAD-7).(Change from Baseline GAD-7 at 5 weeks)

Study Sites (1)

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