NCT00052065已完成1 期
Phase 1-2a Dose-Ranging Study of TLK286 in Combination With Doxil in Platinum Refractory or Resistant Ovarian Cancer
Telik2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2003年2月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 2
研究概览
简要总结
This is a dose-ranging, open-label, Phase 1-2a study of TLK286 in combination with Doxil in patients with platinum refractory or resistant ovarian cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Histologically or cytologically confirmed diagnosis of epithelial cancer of the ovary, fallopian tube cancer or primary peritoneal cancer
- •Recurrent epithelial ovarian cancer or persistent disease following primary treatment
- •At least one, but no more than four, prior platinum-containing chemotherapy regimens
- •At least one prior taxane-containing regimen
排除标准
- •A history of prior malignancy except for adequately treated carcinoma in situ of the uterine cervix, basal cell or squamous cell skin cancer, or other cancer for which the patient has been disease-free for 2 years
- •Known leptomeningeal metastases or carcinomatous meningitis
- •Have received prior Doxil or other liposomal doxorubicin
- •Having received whole pelvis radiation therapy
研究者
研究点 (2)
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