Pharmaceutico Analytical Study Of Panchawalkal Based Toothpaste And Its Efficacy In The Management Of Krimidant(Dental Caries)In Comparison With Panchawalkal Kwath Kawala
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Access and compare Efficacy of Panchawalkal Based Toothpaste in the management of Krimedanta in comparison with Panchawalkal Kwath Kawala by using subjective and objective criteria.
研究概览
简要总结
These diseases are categorized as Dantaroga, Dantashoola, Krumidanta(dentalcaries),etc.inAyurveda2.ThePathophysiologyof Krumidanta, mainly points towards the vitiated Vata Dosha causing structural deformity at the tooth surface. Further, it combines with plaque to form dental caries, gingival and periodontal diseases.
Among the three dosha dominant Vata Dosha makes teeth hollow and damages nerves, the food particles and dirt get accumulated inthis cavity and can damage nerves. This results in bad breath and accumulation of bacteria (small Krumi). Teeth starts paining, becomes black, get swollen, becomes mobile with bleeding gums. This syndrome may be called "Krumidanta." (Dental caries) in Ayurveda3.
Symptoms of Krumidanta described in Sushruta Samhita are Dalana / Maharuja / Vedana (toothache), Sheetadanta / Dantaharsha (sensitive teeth), Krishnachidri / Kotha (black caries), Chala danta (mobile), Stravi (pus formation) and Sasanrambho/durgandha yukta Shotha (inflammation with foul smell)4.
Ayurvedahasmentionedvariouseightprincipleswhichis
knownas‘AshtangaAyurveda’.ItincludesKaya,Balaetc.branchesinwhichRasashastraandBhaishajyaKalpanaVigyanaalsoincluded5.
For proper care of teeth, regular use of Kawala, Gandusha Dharana mentioned in Ayurveda and in modern science tooth brushing was described. Rasashastra and Bhaishajya Kalpana includes various pharmaceuticals, analytical and standardization of drugs and its study. In this study, Toothpaste is made up by the help of Panchawalkal and its efficacy in the management of Krumidanta.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1:The patients were diagnosed on the basis of the signs and symptoms of Krimedanta (dental caries).
- •2:Patients having age from 30 to 45 years.
- •3:Patients of both gender,irrespective of their socioeconomical status, education, etc.
排除标准
- •1:Patients of age below 30years and above 45 years.
- •2:Patients having fractured tooth,periodontal abscess andother diseases of oral cavity.
- •3:Pregnancy, Menopause, Chronic Hormonal diseases like Diabetes Mellitus, hypo/hyperthyroidism, parathyroidism, bone deformities like osteoarthritis, malignancy.
结局指标
主要结局
Access and compare Efficacy of Panchawalkal Based Toothpaste in the management of Krimedanta in comparison with Panchawalkal Kwath Kawala by using subjective and objective criteria.
时间窗: Total duration of medication: 07 Days.
次要结局
未报告次要终点
研究者
DrMahesh Ramesh Waghmare
Ashwin Rural Ayurved College Manchi Hill Sangamner