Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteers

Not Applicable

Not yet recruiting

• Conditions: Health, Subjective
• Interventions: Drug: Mulberry leaf extract 18 mg capsule; Drug: Mulberry leaf extract 12 mg capsule; Drug: Mulberry leaf extract 6 mg capsule; Drug: Placebo capsule

• Registration Number: NCT06488326
• Lead Sponsor: Chulalongkorn University

Brief Summary

Volunteers will be divided into 4 groups which are mulberry leaf extract 6 mg capsule, mulberry leaf extract 12 mg capsule, mulberry leaf extract 18 mg capsule, and placebo capsule group. They will be tested blood glucose levels (taken from the fingertips) before starting. Then, they will take 1 capsule of the sample one time. After taking the sample for 30 minutes, they will take 50 g of sucrose in 250 ml of water in 5 minutes. Then, they will be tested blood glucose levels (taken from the fingertips) at 30, 60, 90, and 120 minutes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-06
• Study First Submitted: 2024-06-28
• Study First Submitted QC: 2024-06-28
• Last Update Submitted: 2024-06-28
• Study Start: 2024-07-01
• Study First Posted: 2024-07-05
• Last Update Posted: 2024-07-05
• Primary Completion: 2024-12-30
• Study Completion: 2025-02-25

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Age 18-60 years
• No diabetes mellitus
• Have blood glucose less than 126 mg/dL
• Wiling to attend the study

Exclusion Criteria

• Take steroids, psychiatric medicine, thiazide diuretic medicine, and beta blocker medicine within 2 weeks before starting of the study
• Take dietary supplement, herbal substance, and weight-loss medicine within 2 weeks before starting of the study
• Uncontrolled diseases
• History of gastrointestinal tract surgery
• Liver and Kidney diseases
• Pregnancy and lactation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mulberry leaf extract 18 mg capsule	Mulberry leaf extract 18 mg capsule	Take one capsule of the sample one time.
Mulberry leaf extract 12 mg capsule	Mulberry leaf extract 12 mg capsule	Take one capsule of the sample one time.
Mulberry leaf extract 6 mg capsule	Mulberry leaf extract 6 mg capsule	Take one capsule of the sample one time.
Placebo capsule	Placebo capsule	Take one capsule of the sample one time.

Primary Outcome Measures

Name	Time	Method
Blood glucose	120 minutes	Volunteers will be measured the blood glucose using blood glucose meter and strip (accuchek) before and after taking the sample for 30, 60, 90, and 120 minutes.