KCT0005749
Not yet recruiting
未知
The comparison of respiratory depression between propofol and propofol in combination with dexmedetomidine for deep sedation during total knee replacement under spinal anesthesia: a prospective randomized controlled trial
The Catholic University of Korea, Daejeon St. Mary's Hospital0 sites82 target enrollmentTBD
ConditionsNot Applicable
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not Applicable
- Sponsor
- The Catholic University of Korea, Daejeon St. Mary's Hospital
- Enrollment
- 82
- Status
- Not yet recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •American society of anesthesiology (ASA) physical status 1, 2, 3
- •Age: 50\-80 yrs
- •Patients for total knee replacement surgery under spinal anesthesia
Exclusion Criteria
- •Severe bradycardia, HR \<50 ?/min
- •Severe cardiopulmonary disease, ASA 4??
- •Severe hepatic or renal disease
- •Body mass index \> 35
- •contraindication to spinal anesthesia
- •Allergy to study medicine, propofol, dexmedetomidine
- •History of severe obstructive sleep apnea or a tendency for airway obstruction
- •Refusal of intraoperative sedation
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
The degree of respiratory depression in accordance with the concentration of remimazolamNot ApplicableKCT0006952Ajou University Hospital108
Completed
Not Applicable
respiratory complication in intra-tracheal intubation and Laryngeal Mask (LMA) in neonatesinguinal hernia.K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangreneIRCT2016070126866N2Isfahan University of Medical Sciences88
Completed
Not Applicable
Incidence of respiratory depression associated with administration of intrathecal morphine for cesarean deliverycesarean deliveryJPRN-UMIN000041337Shimane University100
Completed
Phase 3
Incidence of respiratory depression and other side effects within the first 24 hours after administration of 0.2 mg intrathecal morphine to control post-cesarean section pain: A review of 17,659 cases at Thailand’s largest national tertiary referral centerParturients whom underwent cesarean section under spinal block with intrathecal morphineTCTR20180126004one17,659
Recruiting
Not Applicable
A comparison of effects on respiratory function of sugammadex and neostigmine in the reversal of moderate rocuronium-induced neuromuscular blockadePatients undergoing laparoscopic intestinal surgeryJPRN-UMIN000014751Osaka City General Hospital60