Evaluation of antibiotic prophylaxis and therapy in patients undergoing oral and maxillofacial surgery

• Conditions: 5-401 OPS577b OPS5-402 OPS5-403 OPS5-404 OPS5-406 OPS5-407 OPS; S02.6; S02.2; S02.3; Z47.0; S02.4; K07.1; K07.2; Fracture of nasal bones; Anomalies of jaw-cranial base relationship

• Registration Number: DRKS00029280
• Lead Sponsor: niversitätsklinikum Düsseldorf, Klinik für Mund-, Kiefer- und Plastische Gesichtschirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-12-12
• Study Start: 2022-06-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 870

Inclusion Criteria

Secured ICD diagnosis
Sufficient existing documentation
Within the observation period

Exclusion Criteria

Insufficiently documented clinical course
• Outside the observation period

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reaching the minimum number of n=350 from patient data in the UKD database over an observation period from January 1st, 2018 to July 1st, 2020 (dysgnathia: December 12th, 2020), deadline for establishing the guidelines: June 1st, 2019.<br>Aim for a sample size that is as balanced as possible, even with smaller case groups such as tumors and augmentations.<br><br>With a balanced ratio of experimental to control group, in order to synthesize a statistically high-quality elaboration on the question of the success of guideline implementation.

Secondary Outcome Measures

Name	Time	Method
Achievement of a heterogeneous distribution between comparison and control group to compare more elective versus more extensive antibiotic prophylaxis and investigation of the effects of this on complications in the course of wound healing.<br>As well as checking the successful establishment of the newly implemented guideline.