Investigation of the influence of transcutaneous spinal direct current stimulation (tsDCS) on the functional connectivity of the somatosensory circuits via functional fMRI.
Not Applicable
- Conditions
- Painhealthy controls
- Registration Number
- DRKS00011606
- Lead Sponsor
- Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
>18 years and <45 years
voluntariness
male
healthy
right-handed
written informed consent
sufficient German language skills
Exclusion Criteria
female gender
left-handed, two-handed
any intake of medication
neurological symptoms
psychiatric disorder
tattoo
diabetes mellitus or polyneuropathy
withdrawal of declaration of consent
staff of principal investigator
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes (post-pre differences) in resting state functional connectivity within anodal and/or cathodal stimulation sessions were compared to changes in connectivity within the sham stimulation session.<br><br>We hypothesize that tsDCS-induced changes in neurophysiological measures might be reflected in spontaneous brain activity in the associated networks using fMRI.<br><br>Design: fMRI - tsDCS for 20min - fMRI
- Secondary Outcome Measures
Name Time Method We investigated tsDCS-induced changes in somatosensory cortical connectivity by using seed-to-voxel-based analyses from the primary somatosensory cortex and the thalamus (e.g. pain circuits) prior and after 20min tsDCS visualized by fMRI.