Efficacy of Marine By-product Hydrolysate on the Reduction of Atopic Dermatitis Symptoms

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria: - Phototype: I to V; - Subjects with atopic skin (with at least 1 visible xerosis + inflammation on the body); - Subjects with a history background of asthma, rhinitis and/or allergic conjunctivitis; - Subjects with SCORAD between 8 and 30 (at least 50% or more having around 8-10); - Subjects with BMI between 20 and 30 kg/m2 (limits included); - Subjects who have not recently participated in another similar study; - Willingness to take supplements for the duration of the study; - Willingness not to use products likely to interfere with the test product (collagen, hyaluronic acid, anti-stress products); - Willingness not to change lifestyle habits; - Willingness to avoid intensive UV exposure; - Use of contraception that should not be modified during the study. - Healthy subject; - Mentally healthy subject according to Investigator's opinion; - Subject having given his/her free informed, written consent; - Subject agrees to taking photograph and then use the image after its pseudonymization; - Subject willing to adhere to the protocol and study procedures; - Subject able to understand the study; - Subject available to attend the study visits. Exclusion Criteria: - Pregnant or nursing woman or woman planning to get pregnant during the study; - Cutaneous marks on the experimental areas, which could interfere with the assessment of skin reactions; - Subjects who have participated in the last 3 months or are currently participating in another clinical trial that may interfere with the evaluation of the primary endpoint (endpoint AD); - Current administration of antibiotics; - Known history of chronic disease such as congenital heart disease, liver or kidney disease, or immune deficiency; - Topical treatment with immunomodulators (tacrolimus or pimecrolimus) in the three months prior to registration; - Application of moisturizing products on the experimental area the day of the inclusion of the study; - Acute or chronic infectious diseases; - Not meet inclusion criteria; - Those undergoing aesthetic medicine (fillers, hyaluronic acid injections, botox) that could interference in the experimental area; - Subjects suffering Alimentary/Eating disorders (i.e. bulimia, psychogenic eating disorders, etc.) - Subjects having frequent stomach burn; - Allergy or intolerance to any ingredient of the experimental food supplement; - Subjects with diabetes mellitus; - Fish and/or iodine allergy; - Intestinal conditions or disorders (Crohn's disease, colitis, irritable bowel syndrome, intestinal malabsorption...) - Recent change, forecast of initiation of an hormonal treatment or change of the usual hormonal treatment during the study or 3 months before the starting of the study; - Subject having undergone a surgery under general anesthesia within the previous month; - Exposure in UVA ray sunbed during the 3 months before the start of the study on the experimental area or during the study; - Subjects protected by the law; - Subject employed by EUROFINS PRODUCT TESTING, COSMETICS & PERSONAL CARE SPAIN, S.L.U.

Exclusion Criteria

Not provided

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
SCORAD (SCORing Atopic Dermatitis)

Secondary Outcome Measures

Name	Time	Method
EASI (Eczema Area and Severity Index);Investigator Global Assessment scale;Corneometer;Transepidermal Water Loss (TEWL);Quality of Life Index - Perceived Stress;Participant's Satisfaction

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