Effects of treated and untreated Allergic Rhinitis on Mood, Cognitive functions and Actual Driving Performance - Rhinitis and Driving

niversiteit Maastricht0 个研究点目标入组 24 人开始时间: 待定最近更新: 2024年5月6日

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•1 Participants must be normal healthy males or females, age between 21 and 45 years, diagnosed with seasonal AR (SAR), also known as Intermittent Rhinitis (ITR) Anti-allergic treatment during the previous season, positive radioallergosorbent test for serum-specific immunoglobulin E or positive skin prick test for tree/ and/or grass- and/or weed pollen.
•2. Participants must be experienced drivers. That is, each shall have held a driver*s license for at least the preceding two years and shall have driven more than 5,000 km/yr (3,000 miles/yr) during that period.
•3.Participants must be in general good health as confirmed by routine clinical and laboratory testing.
•4 Participants must be able and willing to give Informed consent

•1. Participants who have clinically significant abnormal physical findings or vital signs at the Screening physical examination (as determined by the Investigator) which could interfere with the objectives of the study. This includes participants who have any history or symptoms of chronic illness including asthma, history of psychotic disorders, drug addiction or abuse of drugs or alcohol which could interfere with the completion of the study.
•2.Participants requiring any CNS medication during the study, or medication with sedative effects which could interfere with the objectives of the study.
•3.Participants who have taken participated in an investigational drug trial within one month prior to the Screening Visit.
•4. Participants with a history of allergies to more than two classes of medication or who are allergic to or cannot tolerate antihistamines.
•5. Excessive smoking; i.e., more than ten cigarettes per day or the equivalent.
•6. Excessive consumption of beverages containing caffeine; i.e., more than five cups per day.
•7. Participants with active seasonal and/ or perennial allergic rhinitis.
•8. Pregnant or nursing females.

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