Adult ALL Treatment at Diagnosis
Not Applicable
Completed
- Conditions
- Leukemia, Lymphocytic, Acute
- Registration Number
- NCT00537550
- Brief Summary
The present study has been designed to give participating centers the possibility of better understanding the diagnostic and prognostic factors of ALL patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Diagnosis of acute lymphoblastic leukemia (ALL)
- Negative myeloperoxidase stain
- Phenotype T (ALL-T) and B(ALL-B)
Exclusion Criteria
- Creatinine > 2.5mg/dL after adequate hydratation
- LVEF <50%
- Presence of documented infections not responding to antibiotic and/or antifungal therapy
- Presence of concomitant malignant diseases
- Absence of any psychological condition that does not allow to intake high doses of cortisone
- Patients who have received any antineoplastic chemiotherapy for more than 5 days
- Patients who have received any steroids for more than 10 days
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the GIMEMA treatment protocol for adult B-cell ALL patients in NCT00537550?
How does the GIMEMA regimen compare to standard-of-care therapies like Hyper-CVAD in adult ALL treatment outcomes?
Which biomarkers are used for risk stratification and response prediction in the GIMEMA ALL trial NCT00537550?
What are the key adverse events associated with GIMEMA protocols for adult ALL, and how are they managed?
What combination therapies or targeted agents are being explored alongside GIMEMA guidelines for adult ALL treatment?
Trial Locations
- Locations (5)
Az. Ospedaliera S. G. Moscati
🇮🇹Avellino, Italy
Ist.Ematologia e Oncologia Medica L.e A. Seragnoli
🇮🇹Bologna, Italy
Ospedale Reg. A di Summa
🇮🇹Brindisi, Italy
Istituto di Ematologia- Ospedale San Carlo
🇮🇹Potenza, Italy
Policlinico G.B. Rossi
🇮🇹Verona, Italy
Az. Ospedaliera S. G. Moscati🇮🇹Avellino, Italy