Pre-operative study the efficacy of nebulized Dexmedetomidine on blunting hemodynamic changes during intubation and pneumoperitoneum in morbid obese patients during laparoscopic bariatric surgery. Randomized double blind control study
Not Applicable
Not yet recruiting
- Conditions
- Anaesthesia
- Registration Number
- PACTR202308566462034
- Lead Sponsor
- sherif kamal hafez arafa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1-This study will include 90 adult morbidly obese patients of both sex
2- with BMI (30-45),
3-ASA II-III physical status,
4-aged between 20-60 years
5- scheduled for elective laparoscopic bariatric surgery under general anesthesia.
Exclusion Criteria
1-Patients' refusal
2-Decompansated hepatic or renal or cardiac disease
3-Expected difficult airway management
4-Uncontrolled hypertension
5-Psychiatric disease
6-Sever pulmonary disease
7-Patient om opioid, alcohol, beta0 blockers or allergy to any of the study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does nebulized Dexmedetomidine target to blunt hemodynamic changes in morbidly obese patients during laparoscopic bariatric surgery?
How does nebulized Dexmedetomidine compare to standard premedication agents in managing hemodynamic responses during intubation and pneumoperitoneum in morbid obesity?
Are there specific biomarkers that can predict patient response to nebulized Dexmedetomidine for hemodynamic stability in bariatric surgery?
What are the potential adverse events associated with nebulized Dexmedetomidine in morbidly obese patients undergoing laparoscopic bariatric procedures?
What combination therapies or alternative drugs are being explored alongside Dexmedetomidine for optimizing hemodynamic control in high-risk bariatric surgery patients?