comparison of pain relieving efficacy and time duration of errector spinae block with general anaesthesia and multiple drugs analgesia with general anaesthesia in spine surgery

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/04/042221
• Lead Sponsor: Mahatma Gandhi Hospital and Medical College

Brief Summary

post operative pain management is an essential component of anaesthetic management of surgical patient. it ensure patient comfort, fewer cardiac and respiratory complication, early mobilization and hence less chances of deep vein thrombosis. the goal of postoperative pain management is to relieve pain while keeping side effects to a minimum. Even after years of advances, the mainstay of pain therapy is still the opioids. while they are very effective analgesics, opioid also carry with them many undesirable side effects: sedation, respiratory depression, nausea and vomiting, hypotension and and bradycardia, pruritis and inhibition of bowel function. to avoid these newer modalities of pain management are being evaluated. management of acute pain following surgery using multimodal approach is recommended by the American society of Anaesthesiologists whenever possible. In addition to opioids, drugs with differing mechanism of actions target pain pathways resulting in additive and/or synergistic effects. Some of these agents include alpha2 agonists, NMDA receptor antagonists, gabapentinoids, dexamethasone, NSAIDs, acetaminophen, and duloxetine, MgSo4 etc. In regional anaesthesia, errector spinae block for spine surgery is gaining popularity. however, there are few clinical studies on ESPB and its effectiveness and safety are controversial. In view of large number spine surgeries that are conducted in our hospital, we intend to compare efficacy of regional anaesthesia with multimodal analgesia using paracetamol,Mgso4 and dexamethasone to ensure better surgical comfort in patient undergoing spine surgery under general anaesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-20
• Study Completion: 2022-07-30
• Last Update Posted: 2025-02-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.Patient fulfilling criteria of American Society of Anesthesiology (ASA) of Classes I/ II.
• 2.Patient aged 18-65 years of both sexes.
• 3.Patients undergoing elective spine surgeries under general anesthesia.
• 4.Patients giving consent willingly.

Exclusion Criteria

1.Patient with ASA CLASS III, IV & V 2.Refusal of patient 3.Patient with difficult surgical anatomy 4.Local infection at the site of injection 5.History of allergy to opioid or local anesthesia 6.Inability to comprehend or participate in pain scoring system.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
perioperative by haemodynamic variability like BP,HR,SpO2,mean BP and postoperatively by visual analog scale(VAS), if VAS is more than 3 the patient will receive a rescue dose of 2mg/kg of tramadol	1. haemodynamic monitoring baseline | 2.at the time of induction | 3.at the time of block/multimodal analgesia | 4.15min affter block/mma | then every 15min till extubation | 5. post extubation | 6. post extubation vitals and VAS score monitoring every 5min. if more than 3 VAS score then injection tramadol 2mg//kg/bw.

Secondary Outcome Measures

Name	Time	Method
mean blood pressure, heart rate, patient satisfaction	perioperatively

Trial Locations

Locations (1)

Mahatma Gandhi Hospital and Medical College; 🇮🇳 Jaipur, RAJASTHAN, India

Mahatma Gandhi Hospital and Medical College

🇮🇳Jaipur, RAJASTHAN, India

Dr Ayush Gupta

Principal investigator

8009420240

ayushgupta20061992@gmail.com