Effects of Brain-stimulation on Memory and Memory Awareness
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 216
- 试验地点
- 2
- 主要终点
- Memory Control Advantage Index
研究概览
简要总结
When people learn and remember information, it is often accompanied by a feeling of subjective confidence about whether or not information has been learned and accurately remembered. These subjective feelings of confidence are often related to actual memory performance, but are sometimes incorrect. The investigators have previously shown that applying high definition transcranial direct current stimulation (HD-tDCS) over the dorsolateral prefrontal cortex leads to more accurate feelings of subjective confidence, at least when subjects are asked for their confidence about future memory performance. Accurate confidence judgments are useful in that they may later subsequent behavior, and inaccurate ones may be costly. For example, a student who erroneously believes that studied material was learned may stop studying and not do well on a test. Individuals who have a feeling-of-knowing about the answer to a general knowledge question will continue to search their memory, whereas individuals who do not have a feeling-of-knowing will stop searching their memory. Individuals who are confident they know the answer to a question are more likely to answer it. In this study, the experimenters are testing the effects of brain stimulation on subjective awareness of memory (termed metamemory monitoring) and how people use those subjective judgments (termed metamemory control). The approach taken is to have participants visit the laboratory on 3 visits and receive brain stimulation while completing memory and metamemory tasks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy, right-handed adults ages 18-
- •English spoken since age
- •Normal or corrected-to-normal vision.
排除标准
- •Participants will be excluded if they have chronic skin disease or a medical skin condition, or an unhealed open wound on the scalp, face, neck, or forehead near the electrode location.
- •Participants will be excluded if they self-report significant medical, neurological, or psychiatric illness and/or a history of substance abuse
结局指标
主要结局
Memory Control Advantage Index
时间窗: Through study completion, an average of 3 weeks
This indexes the memory advantage for choosing which general knowledge question one receives a hint about the answer to versus having the experimenter choose which general knowledge question one receives a hint about the answer. The investigators will subtract the proportion of correctly recognized general knowledge answers for experimenter-chosen questions from the proportion correctly recognized for participant-chosen questions
次要结局
- semantic recognition as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
- semantic recall as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
- Feeling-of-knowing ratings and their accuracy(Through study completion, an average of 3 weeks)
研究者
Elizabeth Chua
Associate Professor
Brooklyn College of the City University of New York
