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临床试验/NCT03693729
NCT03693729Unknown不适用

Effects of Brain-stimulation on Memory and Memory Awareness

Brooklyn College of the City University of New York2 个研究点 分布在 1 个国家目标入组 216 人开始时间: 2018年9月3日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
216
试验地点
2
主要终点
Memory Control Advantage Index

研究概览

简要总结

When people learn and remember information, it is often accompanied by a feeling of subjective confidence about whether or not information has been learned and accurately remembered. These subjective feelings of confidence are often related to actual memory performance, but are sometimes incorrect. The investigators have previously shown that applying high definition transcranial direct current stimulation (HD-tDCS) over the dorsolateral prefrontal cortex leads to more accurate feelings of subjective confidence, at least when subjects are asked for their confidence about future memory performance. Accurate confidence judgments are useful in that they may later subsequent behavior, and inaccurate ones may be costly. For example, a student who erroneously believes that studied material was learned may stop studying and not do well on a test. Individuals who have a feeling-of-knowing about the answer to a general knowledge question will continue to search their memory, whereas individuals who do not have a feeling-of-knowing will stop searching their memory. Individuals who are confident they know the answer to a question are more likely to answer it. In this study, the experimenters are testing the effects of brain stimulation on subjective awareness of memory (termed metamemory monitoring) and how people use those subjective judgments (termed metamemory control). The approach taken is to have participants visit the laboratory on 3 visits and receive brain stimulation while completing memory and metamemory tasks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy, right-handed adults ages 18-
  • English spoken since age
  • Normal or corrected-to-normal vision.

排除标准

  • Participants will be excluded if they have chronic skin disease or a medical skin condition, or an unhealed open wound on the scalp, face, neck, or forehead near the electrode location.
  • Participants will be excluded if they self-report significant medical, neurological, or psychiatric illness and/or a history of substance abuse

结局指标

主要结局

Memory Control Advantage Index

时间窗: Through study completion, an average of 3 weeks

This indexes the memory advantage for choosing which general knowledge question one receives a hint about the answer to versus having the experimenter choose which general knowledge question one receives a hint about the answer. The investigators will subtract the proportion of correctly recognized general knowledge answers for experimenter-chosen questions from the proportion correctly recognized for participant-chosen questions

次要结局

  • semantic recognition as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
  • semantic recall as assessed by a general knowledge task(Through study completion, an average of 3 weeks)
  • Feeling-of-knowing ratings and their accuracy(Through study completion, an average of 3 weeks)

研究者

发起方
Brooklyn College of the City University of New York
申办方类型
Other
责任方
Principal Investigator
主要研究者

Elizabeth Chua

Associate Professor

Brooklyn College of the City University of New York

研究点 (2)

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