The effect of maternal IV hydration vs Oral hydration on amniotic fluid index in oligohydramnios, A randomised controlled trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- To compare the effect of maternal IV hydration with oral hydration on the amniotic fluid index (AFI) in cases of oligohydramnios diagnosed with ultrasonography
研究概览
简要总结
Oligoamnios, defined as an amniotic fluid index (AFI) less than or equal to 5 cm, is associated with intrauterine growth restriction, umbilical cord compression, fetal distress, and increased cesarean rates. Maternal hydration, oral and intravenous (IV) is a simple, non-invasive intervention to improve AFI, but comparative efficacy remains underexplored. To compare the effects of maternal IV and oral hydration on AFI in pregnancies complicated by oligoamnios. In this hospital-based randomized controlled trial, 60 pregnant women (28–40 weeks gestation) with oligoamnios were assigned to IV hydration (2 L of 0.45% normal saline over 2 hours) or oral hydration (2 L of water over 2 hours). AFI was measured before and after intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •Singleton pregnancy Gestational age between 28 to 40 weeks Diagnosed with AFI less than 8 cm Willingness to participate and provide informed consent.
排除标准
- •Multiple pregnancies Fetal congenital anomalies Ruptured membranes or active labour Any condition where oral or IV hydration is contraindicated.
结局指标
主要结局
To compare the effect of maternal IV hydration with oral hydration on the amniotic fluid index (AFI) in cases of oligohydramnios diagnosed with ultrasonography
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Syeda Sarah Bibi Fatima
Jawaharlal Nehru Medical College, Belagavi, Karnataka