Effects of Non-drug Therapy on Cognitive Function in Healthy Individuals and Patients With First Episode Depression

Central South University1 个研究点分布在 1 个国家目标入组 120 人2020年7月30日

适应症Depressive Disorder

概览

阶段: 不适用
干预措施: 未指定
疾病 / 适应症: Depressive Disorder
发起方: Central South University
入组人数: 120
试验地点: 1
主要终点: The change of cerebellar electrical stimulation on cognitive function in healthy individuals
状态: 已完成
最后更新: 3年前

概览研究者入排标准结局指标研究点相似试验

概览

简要总结

Mindfulness training, relaxation training, and cerebellar electrical stimulation were used to intervene in the cognitive function of healthy individuals and individuals with first episode depression

详细描述

In this proposed study,the investigators will evaluate the effects of different non-pharmacological interventions (physical/psychological) on emotion-related cognitive function.This project will use a variety of intervention methods to conduct research in healthy individuals and patients with mood disorders. The main intervention methods include: (1) mindfulness training;(2) relaxation training;(3) cerebellar electrical stimulation. The study will recruit 80 healthy subjects and 40 first-episode depression patients. The study consisted of three steps: First, subjects filled in personal data and completed the first screening, randomly assigned groups, and filled in the pre-intervention questionnaire;Second, give a one-time non-drug intervention (mindfulness training, relaxation training or cerebellar electrical stimulation);Step 3: After the intervention, the subjects filled in the post-intervention questionnaire and completed the cognitive task test.Clinical efficacy and safety assessment will be done at first time. The specific aims are to evaluate the effect of non-drug therapy on cognitive function in healthy individuals and patients with first episode depression. and the behavior was evaluated by cognitive function task.

注册库

clinicaltrials.gov

开始日期

2020年7月30日

结束日期

2022年6月30日

最后更新

3年前

研究类型

Interventional

研究设计

Parallel

性别

All

研究者

发起方

Central South University

责任方

Principal Investigator

主要研究者

Jian-Jun Ou

Principal Investigator

Central South University

入排标准

入选标准

•Healthy individuals group:
•Aged between 16 and 34;
•Does not meet the criteria of the DIAGNOSTIC and Statistical Manual of Mental Disorders, DSM-5,Does not meet the diagnosis of depression, bipolar disorder and other mental disorders.
•First episode depression group:
•Aged between 16 and 34;
•Clinically diagnosed as having depression according to the DIAGNOSTIC and Statistical Manual of Mental Disorders (DSM-5);
•First attack, not taking medicine, no risk of serious suicide NSSI.

排除标准

•There are serious physical diseases, such as epilepsy, brain trauma, intracranial space-occupying lesions, severe audiovisual disorders, congenital heart disease, etc.;
•Both Hamilton Depression Scale and Beck Depression Self-Rating Scale indicate severe depression or severe mental illness;
•Affected by mental illness, it is difficult to conduct smooth and effective verbal communication and psychological measurement operation.