MedPath

Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Health Staff

Not Applicable
Recruiting
Conditions
Smoking Cessation
Interventions
Drug: Music intervention
Registration Number
NCT06130423
Lead Sponsor
Poitiers University Hospital
Brief Summary

The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 50 health staff smokers. This pilot multi-method study will combine the methodology of clinical trial with qualitative techniques used in social sciences to show the interest of a digital music therapy tool, adapted to a health staff audience.

Detailed Description

The participants will be recruited at the Clinical Investigation Center (CIC) of the University Hospital of Poitiers. At baseline visit, they will be randomly 1:1 assigned to receive either music therapy and NRT or NRT alone for 3 months.

During the 3 months after Target Quit Date (TQD) , 3 visits will be performed by practitioners and nurses at the CIC. They will register smoking status of the participant, exhaled carbon monoxide concentration, body weight and all adverse events. Participants will answer questionnaires (FTCQ-12,Hospital Anxiety and Depression Scale ( HAD), Minnesota Nicotine Withdrawal Scale (MNWS), Impulsive Behavior Scale (UPPS), State-trait Anxiety Inventory Forme Y (STAI-Y)).

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Health staff,
  • Age >= 18 years
  • Smoking more than 10 cigarettes per day for at least 6 months
  • motivated to quit smoking
  • without legal tutors or subordination
  • affiliated to a health insurance system as required by the French law on biomedical research
  • written informed consent for participation in the study
Exclusion Criteria
  • Roommates and couples
  • NRT contraindication
  • unstabilised depression
  • psychosis and/or cognitive disorder and/or mental retardation
  • substance misuse or alcohol dependence
  • smoking-cessation medication (NRT, bupropion) or undergoing cognitive-behavioral therapy or hypnotherapy for smoking cessation in the last 3 months
  • electronic cigarette for smoking cessation in the last 3 months
  • participating in a study up to visit 4
  • Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Music intervention and NRTNicotine replacementThe rhythm of the music sessions will be 2 per week in the first month, 1 per week in the second month and 1 every 15 days in th third month, music intervention will be associated to NRT.
NRT GroupNicotine replacementNicotine Patch, Nicotine Gum as in the intervention group, the physician will adapt the type of NRT according to the patient's smoking profile.
Music intervention and NRTMusic interventionThe rhythm of the music sessions will be 2 per week in the first month, 1 per week in the second month and 1 every 15 days in th third month, music intervention will be associated to NRT.
Primary Outcome Measures
NameTimeMethod
Assess if Music therapy associated to NRT decrease tabacco craving compared to NRT aloneMonth 1

Score of French Version of the Tabacco Craving Questionnaire-12 (FTCQ-12). It consist of 12 questions, each rated on a likert-type scale with 7 response options. Lower scores mean a better outcome

Secondary Outcome Measures
NameTimeMethod
Test the feasibility of such a program in smoking cessationMonth 3

Music therapy sessions compliance. Number and reasons for non attending music therapy sessions

Evaluate the evolution of AnxietyMonth [1;2;3]

STAI-Y (Form-Y of the State-Trait Anxiety Inventory) score. It consist of two 20-item scales providing separate measures of state and trait anxiety (S-Anxiety and T-Anxiety, respectively). On a 4-point Likert scale (1-4), a score equal to 4 indicates the presence of a higher level of anxiety.

Evaluate the efficacy of the intervention on smoking cessationMonth [6;12]

Self reported abstinence or smoking reduction \> or = 50%

Evaluate the evolution of tabacco cravingMonth [2;3]

Score of French Version of the Tabacco Craving Questionnaire-12 (FTCQ-12). It consist of 12 questions, each rated on a likert-type scale with 7 response options. Lower scores mean a better outcome

Evaluate the evolution of nicotine withdrawal symptomsMonth [1;2;3]

MNWS (Minnesota Nicotine Withdrawal Scale) score. It consist of 8 questions, each rated on a likert-type scale with 0-4 response options. Lower scores mean a better outcome.

Evaluate the evolution of impulsivityMonth [1;2;3]

UPPS (Impulsive Behavior Scale) score. It consist of 20 questions, each rated on a likert-type scale with 1-4 response options. Lower scores mean a better outcome.

Trial Locations

Locations (1)

CHU Poitiers / CIC

🇫🇷

Poitiers, France

© Copyright 2025. All Rights Reserved by MedPath