Misoprostol for Second Trimester Pregnancy Termination
Phase 2
Completed
- Conditions
- Intra Uterine Fetal Death
- Interventions
- Procedure: termination of second trimester pregnancy
- Registration Number
- NCT02669420
- Lead Sponsor
- Assiut University
- Brief Summary
The majority of second-trimester pregnancy termination performed in the United States are performed surgically by dilation and evacuation. The frequency of induction of abortion increases as gestational age advances. In the late second trimester and early third trimester, induction is the primary method of termination in cases of fetal abnormalities. In many other countries, however, induction is the primary method of abortion throughout the second trimester
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 180
Inclusion Criteria
- Pregnancy 13-24 weeks.
- Women with indication for termination of the pregnancy due to intra uterine fetal death
Exclusion Criteria
-Pregnancy before 13 weeks.
- Pregnancy beyond 24 weeks.
- Women with scared uterus.
- Known hypersensitivity for misoprostol.
- Refusal of the woman to participate.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description extra amniotic misoprostol termination of second trimester pregnancy misoprostol dissolved in warm saline , become dissolute misoprostol saline solution(200 microgram every 4 hours) vaginal misoprostol termination of second trimester pregnancy misoprostol tablet soaked with distilled water and inserted in the posterior fornix of the vagina( 200 microgram every 4 hours)
- Primary Outcome Measures
Name Time Method mean duration from the initial misoprostol dose until complete fetal expulsion 24 hours
- Secondary Outcome Measures
Name Time Method