Effect of salt fortified with vitamins and minerals among wome

Not Applicable

• Registration Number: CTRI/2022/02/040333
• Lead Sponsor: Dr Christine McDonald

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 February 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) 18-49 years of age;

2) Not currently pregnant (self-reported);

3) Not severely anemia (defined as a hemoglobin concentration < 8 g/dL);

4) Not planning to become pregnant within the next year;

5) Permanent resident of the study village with no plans to move or travel outside the village for more than 4 weeks over the next 12 months;

6) No serious health problems that requires regular visits to a health facility;

7) Willingness to use refined salt provided by the study as a primary source of household discretionary salt.

Exclusion Criteria

1) Age is less than 18 or more than 49 years;

2) Pregnant at the time of enrolment(self-report) or planing to became pregnant within the next year;

3) Severely anemia (i.e. hemoglobin concentration < 8 g/dL);

4) Not a permanent resident of the study area;

5) Planning to leave the study area for at least one month over the study period;

6) Serious health problem that interferes with eating practices and/or requires hospitalization;

7) Unwilling to use refined salt provided by the study as a primary source of household discretionary salt.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in mean concentrations of biomarkers of the following micronutrients and the corresponding change in the prevalence of each micronutrient deficiency: iron: serum ferritin and soluble transferrin receptor; anemia: hemoglobin; zinc: serum zinc, nail zinc; vitamin B12; serum vitamin B12, methylmalonic acid, and holo-transcobalamin; and plasma homocysteine; folate: red blood cell folate; iodine: serum thyroglobulin and urinary iodine.Timepoint: 24 Months from the start of enrolment

Secondary Outcome Measures

Name	Time	Method
Change in the abundance and diversity of the gut microbiome <br/ ><br>Timepoint: 24 Months from the start of enrolment