The effectiveness of multidimensional family therapy (MDFT) versus cognitive behavioural therapy (CBT) in Dutch adolescents with a cannabis use disorder

Not Applicable

Completed

• Conditions: DSM-IV cannabis use disorder; Mental and Behavioural Disorders; Mental and behavioural disorders due to psychoactive substance use

• Registration Number: ISRCTN00179361
• Lead Sponsor: The Netherlands Ministry of Health, Welfare and Sport (Netherlands)

Brief Summary

2016 results in https://pubmed.ncbi.nlm.nih.gov/27006273/ (added 18/12/2020)

Detailed Description

Not available

Study Timeline

• Study Completion: 2010-11-01
• Study Start: 2011-03-17
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 109

Inclusion Criteria

1. A history of cannabis abuse or cannabis dependency based on Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) in at least the year preceding the baseline assessment
2. Recent, regular use of cannabis, as indicated by self-reported cannabis consumption:
2.1. On two or more days a week during the three months preceding the start of the study
2.2. On two or more days a week during the three months preceding the entry of a controlled environment, provided that the controlled environment directly preceded the start of the study and started not longer ago than 90 days before the start of the study
3. Age ranging from 13 to 18 years
4. At least one (step) parent or legal guardian able and willing to participate in the treatment and in the required study assessments
5. Written informed consent, by both the adolescent and his or her parent or legal guardian

Exclusion Criteria

1. Mental retardation, acute psychosis or acute suicidality
2. Inpatient or opioid substitution treatment is required, according to clinical judgement
3. Living outside the catchment area of the treatment centre
4. Inability to understand the Dutch language
5. Participation in another trial aimed at reduction of psycho-active substance use or delinquent behaviour

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Study assessments take place at baseline and at three, six, nine and 12 months (end-point) following baseline.<br> 1. Frequency of cannabis use (i.e. number of cannabis using days and number of joints smoked) in the 90 days preceding the month 12 assessment, based on the timeline follow back (TLFB) calender method. The study data are analysed using an intent-to-treat approach, in which all patients are included that were notified about their group allocation after randomisation.<br><br> Efficacy of MDFT vs CBT in terms of the primary outcome measure is analysed by means of a 2 (treatment group: MDFT vs CBT) x 2 (time: baseline vs month 12) repeated measures MANOVA, using the baseline and month 12 datasets.<br>