Dietary Sodium Intake in Children on Chronic Dialysis

Recruiting

• Conditions: Chronic Dialysis in Children

• Registration Number: NCT06165640
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Cardiovascular disease is common in patients with end-stage renal disease that began in childhood, and volume overload plays a key role in the development of hypertension, left ventricular hypertrophy (LVH) and alterations. cardiovascular disease in this population. Thus, inter-dialytic weight gain is correlated with blood pressure and left ventricular mass index in children on hemodialysis (HD). Significant inter-dialytic weight gain in dialysis patients is largely due to thirst secondary to salt ingestions: attempts at water restriction without concomitant sodium restriction will probably be in vain. Additionally, sodium overload negatively affects blood pressure and cardiovascular status through various mechanisms unrelated to volume expansion.

Soda extraction by dialysis is often difficult, and sodium control is largely dependent on restricting dietary sodium intake. Some studies in adults have shown that a low sodium diet reduced inter-dialytic weight gain, reduced intra-dialytic complications, improved blood pressure values, and lowered index. left ventricular mass and mortality in dialysis patients.

For children with chronic kidney disease, data from the American Chronic Kidney Disease (CKiD) study show that the median sodium intake in children without dialysis with chronic kidney disease exceeds the maximum recommended intakes for all patients. age groups.

No study to date has investigated the average dietary sodium intake of children on dialysis. And, more importantly, the relationship between dietary sodium intake and cardiovascular morbidity has never been studied in children on dialysis.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-25
• Status Verified: 2022-12
• Study First Submitted: 2022-12-13
• Primary Completion: 2023-12
• Study First Submitted QC: 2023-12-08
• Last Update Submitted: 2023-12-08
• Study First Posted: 2023-12-11
• Last Update Posted: 2023-12-11
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the average dietary intake of sodium (Na+) in a population of children on chronic dialysis.	Files analysed retrospectively from January 1, 2019 to February 28, 2021 will be examined	The average dietary intake of sodium (Na+) is calculated according to the formula: sodium salt content (g) = Sodium (g) × 2.54

Trial Locations

Locations (1)

Service de Pédiatrie 1 - CHU de Strasbourg - France; 🇫🇷 Strasbourg, France