AAA-CTA Cohort Registry

Recruiting

• Conditions: Abdominal Aortic Aneurysm; Image

• Registration Number: NCT07039825
• Lead Sponsor: RenJi Hospital

Brief Summary

The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and outpatient populations with abdominal aortic aneurysm.

Detailed Description

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder characterized by irreversible dilation of the abdominal aorta, posing a significant risk of rupture and catastrophic hemorrhage, with mortality rates reaching 65-85% upon rupture. Given the often asymptomatic nature of AAA until rupture, early detection and precise monitoring are critical to prevent fatal outcomes, underscoring the urgent need for reliable diagnostic tools.

Computed tomography angiography (CTA) has emerged as a gold-standard non-invasive imaging technique, offering high-resolution visualization of AAA morphology, including aneurysm diameter, wall thickness, thrombus formation, and spatial relationship to adjacent structures, which are essential for accurate diagnosis, rupture risk stratification, and surgical planning.

This study aims to investigate the precision and clinical utility of CTA in AAA measurement, with the potential to optimize screening protocols, improve intervention timing, and ultimately reduce AAA-related mortality.

By establishing standardized CTA-based assessment criteria, this research may contribute to enhanced diagnostic workflows, better patient risk stratification, and more personalized treatment strategies, thereby addressing a critical gap in vascular disease management.

Study Timeline

• Study Start: 2020-01-01
• Status Verified: 2025-06
• Study First Submitted: 2025-06-18
• Study First Submitted QC: 2025-06-18
• Last Update Submitted: 2025-06-18
• Study First Posted: 2025-06-26
• Last Update Posted: 2025-06-26
• Primary Completion: 2027-05-01
• Study Completion: 2027-05-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Patients with abdominal aortic aneurysm who visited the study hospital.
2. Patients included should have computed tomography angiography data.

Exclusion Criteria

1. Patients who declined participation, cases with incomplete or missing clinical data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maximal abdominal aortic diameter	1 month	The images of computed tomography angiography on abdominal aortic aneurysm are collected and the maximal diameter of abdominal artery is measured by medical specialists.

Secondary Outcome Measures

Name	Time	Method
Mortality	1 month	The death of AAA patients is recorded and mortality is calculated.
Other characteristics of AAA morphology	1 month	Through CTA images, the existence of ulcer, mural thrombus is judged, and the length of AAA is measured by medical specialists.
Rupture	1 month	The images of computed tomography angiography on abdominal aortic aneurysm are collected and the rupture of AAA is judged by medical specialists.

Trial Locations

Locations (1)

Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University; 🇨🇳 Shanghai, China