Comparison of pain levels in nasopalatine nerve blocks using two different techniques

Not Applicable

• Conditions: Pain; N02.421.240.190; Dental Caries

• Registration Number: RBR-9h2kdm9
• Lead Sponsor: niversidade Federal de Sergipe

Brief Summary

Minimizing discomfort during dental anesthetic injection may favor patient compliance with dental treatment. The aim was to compare pain levels between the conventional injection and the Morpheus® device for the nasopalatine nerve block during the puncture, needle introduction, and local anesthetic (LA) deposition. A crossover, double-blind, randomized clinical trial was carried out involving 32 participants. Group I comprised the conventional syringe (control group), while Group II comprised the Morpheus® device (experimental group). The total volume of LA administered was 0.6 mL for both techniques. The study was developed in two sessions, two weeks apart. The pain was assessed using a 100-mm Visual Analog Scale (VAS). The intragroup analyses were performed using the Friedman’s test and Durbin-Conover's post hoc test. The Wilcoxon test was used for intergroup analyses. The significance level was set at p < 0.05. Intragroup analyses showed statistical differences within Group I and II (p < 0.001 and p = 0.003, respectively). All the evaluated moments of both injection techniques differed statistically, except between the needle introduction and LA deposition moments in Group II (p = 0.526). In the intergroup analyses, participants of Group I presented higher pain levels, experiencing the highest pain at the LA deposition moment (median 58; 46 - 62). Pain levels were statistically significant between all the corresponding moments of the groups (p < 0.001). Computerized injection with the Morpheus® can be effectively employed to increase comfort during anesthetic injections and patient compliance with dental treatments

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-06-27
• Study Start: 2022-08-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Both genders; age between 18 and 30 years; any ethnicity; any marital status; any nationality; any place of birth; with previous experience of local anesthesia without intercurrences; not having undergone infiltrative anesthesia in the region in the two weeks prior to the study; and not having used any medication capable of altering pain perception in the two weeks prior to the study

Exclusion Criteria

Age lower than 18 years or higher than 30 years old; pregnant or lactating women; history of hypersensitivity to the drugs used in the study; alcohol abuse or drug dependence; psychiatric disorders or systemic diseases; being under treatment with CNS-acting drugs; use of drugs capable of altering pain perception in the two weeks preceding the study; and moderate anxiety or higher (over 9), based on Corah's Dental Anxiety Scale

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected outcome: It is expected to find lower levels of pain during nasopalatine nerve block with the Morpheus® device during puncture, needle insertion and anesthetic deposition, verified by means of the Visual Analog Scale immediately after the anesthetic injection;Obtained outcome: It was observed statistically lower pain levels during nasopalatine nerve block with the Morpheus® device during the puncture, needle introduction, and local anesthetic deposition, verified by means of the Visual Analog Scale immediately after the anesthetic injection

Secondary Outcome Measures

Name	Time	Method
o secondary outcomes are expected