Magnesium Effect on Embryonal PR Interval
Not Applicable
- Conditions
- Preterm Labor
- Registration Number
- NCT03047304
- Lead Sponsor
- Rambam Health Care Campus
- Brief Summary
Magnesium is a known treatment for neuroprotection in preterm labor before 32 week of gestation. High concentration of Magnesium in the blood stream known as cause of conduction abnormalities and ECG changes such us prolonged QT, QRS and PR in about. The goal of our work is to evaluate the PR intervals in embryos after maternal treatment with magnesium during preterm labor.
- Detailed Description
We will recruit 25 woman with threaten preterm labor, magnesium blood level and PR interval will be evaluated before magnesium loading dose (4gr) and 20 minutes after the loading dose.
PR interval will be evaluated by Mitral-Aorta Doppler.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 25
Inclusion Criteria
- Women at risk for preterm labor before 32 week of gestation
Exclusion Criteria
- Fetal malformations
- Maternal Lupus
- Fetal conduction abnormalities
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Prolonged PR interval 20 min after magnesium treatment PR will be measured by Mitral-aorta doppler
- Secondary Outcome Measures
Name Time Method