Comparison of Analgesic Efficacy of Ultrasound Guided Erector Spinae Plane Block With Port Site Infiltration Following Laparoscopic Cholecystectomy
Overview
- Phase
- Not Applicable
- Intervention
- Erector spinae plane block
- Conditions
- Postoperative Pain
- Sponsor
- Assiut University
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- Total postoperative opioid consumption.
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
To compare the efficacy of ultrasonography (USG)-guided bilateral Erector spinae plane block (ESPB) with port-site infiltration using bupivacaine for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both Erector spinae plane block and port-site infiltration are effective in providing post-operative analgesia.
Investigators
Magdy Mohammed Mahdy Sayed
Principal Investigator
Assiut University
Eligibility Criteria
Inclusion Criteria
- •patients with the American Society of Anesthesiologists (ASA) physical status I/II,
- •Age between 18 and 60 years with a body mass index (BMI) of 18-35 kg/m2,
- •Patients scheduled for elective laparoscopic cholecystectomy.
Exclusion Criteria
- •Allergy to local anaesthetics,
- •Infection at the site of injection,
- •, Coagulopathy,
- •Chronic pain syndromes,
- •Prolonged opioid medication,
- •Patients who received any analgesic 24 h before surgery
Arms & Interventions
Erector spinae plane block
ultrasound guided ESP Block after anaesthesia induction
Intervention: Erector spinae plane block
Erector spinae plane block
ultrasound guided ESP Block after anaesthesia induction
Intervention: Ultrasound machine (Mindray DP 9900 plus; Mindray Bio-Medical Electronics, Shenzhen, China)
Erector spinae plane block
ultrasound guided ESP Block after anaesthesia induction
Intervention: Bupivacaine 0.5%
Erector spinae plane block
ultrasound guided ESP Block after anaesthesia induction
Intervention: Lidocaine 2%
Port site infiltration technique
After the induction of anaesthesia, pre-incisional port-site infiltration will be performed by the same surgeon every time with 20 ml of Local anesthetic (LA) mixture that will be divided equally between port sites
Intervention: Port site infiltration
Port site infiltration technique
After the induction of anaesthesia, pre-incisional port-site infiltration will be performed by the same surgeon every time with 20 ml of Local anesthetic (LA) mixture that will be divided equally between port sites
Intervention: Bupivacaine 0.5%
Port site infiltration technique
After the induction of anaesthesia, pre-incisional port-site infiltration will be performed by the same surgeon every time with 20 ml of Local anesthetic (LA) mixture that will be divided equally between port sites
Intervention: Lidocaine 2%
Outcomes
Primary Outcomes
Total postoperative opioid consumption.
Time Frame: 24 hours postoperatively
Nalbuphine consumption in mg.(equivalent to morphine dose)
Secondary Outcomes
- Pain scores;Numerical Rating Scale (NRS) at rest and when coughing(at 1, 2,4 , 8, 16 and 24 hours postoperatively.)
- •Cumulative postoperative analgesic consumption(24 hours postoperatively)
- •Heart Rate (HR)(Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery)
- •Mean Arterial Pressure (MAP)(Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery)
- Incidence and severity Postoperative nausea & vomiting (PONV).(24 hours postoperatively)