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Treatment strategy in elderly patients with cancer

Recruiting
Conditions
Diagnosis of advanced cancer of colorectum, breast or prostateGemetastaseerd Colorectaal-, borst- of prostaatkanker
Registration Number
NL-OMON27004
Lead Sponsor
H.M.W. Verheul, MD, PhDTelephone: 0031-20-4444321Email: h.verheul@vumc.nl
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
85
Inclusion Criteria

Age older 70 years

- Diagnosis of advanced cancer of colorectum, breast or prostate

Exclusion Criteria

- Presence of cytopenia due to iron-, vitamin B12 and folic acid deficiency or hemolysis, unless adequately supplemented.

- Creatinine clearance ¡Ü 30 ml/min

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
-Toxicity of treatment due to any cause<br /><br>- Prevalence of MDS/IDUS in the studied group of patients
Secondary Outcome Measures
NameTimeMethod
- Prevalence of sarcopenia in the studied group of patients<br /><br>- (Termination, postponement or dose modification) of treatment due to any cause<br /><br>- Overall survival<br>- Response to treatment<br>• Progression free survival<br>• Difference in combination therapy versus monotherapy<br>• Quality of life<br>• Pharmacokinetics
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