Emotional learning and pain in fibromyalgia
- Conditions
- fibromyalgiamusclejoint or bone pain10028393
- Registration Number
- NL-OMON37875
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Fibromyalgia patients will have a diagnosis of primary fibromyalgia according to the American College of Rheumatology classification criteria (Wolfe et al., 1990).
Control participants will be age-matched to fibromyalgia patients and will be healthy and pain-free as determined by a general health questionnaire.
All subjects will be adults 18 years or older
Speak Dutch fluently
The inability to give informed consent
A serious neurological or psychiatric condition besides fibromyalgia
Current participation in another research protocol that could interfere or influence the outcome measures of the present study
Current use of sedative psychotropic drugs such as benzodiazepines, barbiturates, tricyclic antidepressants, anticonvulsants, sedatives and classical antihistaminics, except amitriptyline in low dosages (up to 50 mg/day).
When there is any serious injury to the body regions to be tested as reported by the research participant.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is the directed forgetting effect (less number of<br /><br>items recalled after the *forget* cue compared to those after the *remember*<br /><br>cue) for the neutral, positive, negative and pain-related words separately in<br /><br>patients with fibromyalgia compared to healthy controls. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary parameters are associations between directed forgetting and: 1) CPM<br /><br>efficacy, and 2) numerical ratings of arousal, valence or personal-relevance of<br /><br>each word.</p><br>