The efficacy of cognitive remediation on processing speed in patients with first episode psychosis

Not Applicable

Completed

• Conditions: Psychosis; Mental and Behavioural Disorders; Unspecified nonorganic psychosis

• Registration Number: ISRCTN17220814
• Lead Sponsor: Public Service Department of Malaysia

Brief Summary

2019 Results article in https://doi.org/10.35940/ijitee.L1110.10812S219 results (added 09/12/2020) 2019 Results article in http://sersc.org/journals/index.php/IJAST/article/view/2443 results (added 09/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-08-17
• Study Completion: 2019-10-01
• Last Update Posted: 3 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

1. First-episode psychosis patients with schizophrenia, schizophreniform disorder or schizoaffective disorder at diagnosis and presenting with cognitive deficits
2. Young adults aged 18 to 40
3. Able to read and write in Malay and/or English
4. Written informed consent
5. Fulfil the criteria of cognitive measures, symptomatology and other functioning
6. The symptoms must have been present during the past year including other criteria

Exclusion Criteria

1. Previous diagnosis of mental retardation, psychotic disorder related to a general medical condition or substance-induced psychotic disorder
2. Severe schizophrenia
3. History of any diagnosis of a serious developmental disorder
4. Significant ongoing neurological disorders including epilepsy
5. History of severe head injury
6. Concurrently undergoing other types of cognitive remediation therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive functioning, assessed by neurocognitive assessment through The Brief Assessment of Cognition in Schizophrenia (BACS) at baseline and 8 weeks

Secondary Outcome Measures

Name	Time	Method
Functional outcomes, assessed using functional measures including Schizophrenia Cognition Rating Scale (SCoRS), Social Functioning Scale (SFS), Social and Occupational Functioning Assessment Scale (SOFAS) and Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) at baseline and 8 weeks