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临床试验/ACTRN12615000273583
ACTRN12615000273583已完成4 期

In adults and children undergoing renal transplantation, does dose individualisation of Mycophenolate Mofetil based on a pre-transplant free MPA pharmacokinetic assessment improve post-transplant drug exposure, compared to post transplant exposure on standard fixed doses - as assessed by an increased proportion of patients within therapeutic range from early (day 3-5) post transplant in the dose individualised group, and again at 2 weeks and 3 months post transplant.

Murdoch Children's Research Institute0 个研究点目标入组 56 人开始时间: 2015年3月23日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
56

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Treatment
盲法
Open (masking not used)

入排标准

年龄范围
1 Years 至 o limit(—)
性别
All

入选标准

  • Child and adult participants at or near end-stage kidney disease (ESKD), working up to renal transplantation.

排除标准

  • -Renal transplant protocols not including mycophenolate mofetil
  • -Adult ESKD patients on the cadaveric waiting list deemed unlikely to receive a transplant offer within a 2 year window.

研究者

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