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Clinical Trials/ACTRN12615000273583
ACTRN12615000273583
Completed
Phase 4

In adults and children undergoing renal transplantation, does dose individualisation of Mycophenolate Mofetil based on a pre-transplant free MPA pharmacokinetic assessment improve post-transplant drug exposure, compared to post transplant exposure on standard fixed doses - as assessed by an increased proportion of patients within therapeutic range from early (day 3-5) post transplant in the dose individualised group, and again at 2 weeks and 3 months post transplant.

Murdoch Children's Research Institute0 sites56 target enrollmentMarch 23, 2015

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
End-stage kidney disease
Sponsor
Murdoch Children's Research Institute
Enrollment
56
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 23, 2015
End Date
October 26, 2017
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Child and adult participants at or near end\-stage kidney disease (ESKD), working up to renal transplantation.

Exclusion Criteria

  • \-Renal transplant protocols not including mycophenolate mofetil
  • \-Adult ESKD patients on the cadaveric waiting list deemed unlikely to receive a transplant offer within a 2 year window.

Outcomes

Primary Outcomes

Not specified

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