Effects of Controlled Whole-body Vibration Training on Preventing Falls Among Healthy Population and Ambulatory People With Multiple Sclerosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Georgia State University
- Enrollment
- 58
- Locations
- 1
- Primary Endpoint
- Real life falls
Study Overview
Brief Summary
This study is to investigate the effects of controlled whole-body vibration training on reducing the likelihood of falls among healthy population and people with multiple sclerosis. (NOTE: research not covered by sponsored funding)
Detailed Description
For each population, the participants will be randomized into two groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •For healthy population:
- •Aged between 18 and 75
- •No known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment
- •For people with multiple sclerosis
- •Self-reported multiple sclerosis and confirmed by the physician
- •No significant relapse within the past 8 weeks
- •To be able to walk independently a length of 25 feet
- •Score on Patient Determined Disease Step < 7
Exclusion Criteria
- •Subjects use any sedative of any type.
- •The heel bone density is less than -2.0
Arms & Interventions
Vibration training group
The vibration group will receive 8-week controlled whole-body vibration training as the intervention on the Galileo Med L device
Intervention: Controlled whole-body vibration training (Other)
Placebo training group
The placebo group will receive 8-week placebo training on the Galileo Med L device
Intervention: Controlled whole-body vibration training (Other)
Outcomes
Primary Outcomes
Real life falls
Time Frame: Up to 12 months
Real life falls are monitored for 12 months.
Secondary Outcomes
- Range of motion(Up to 12 months)
- Slip-related falls on treadmill(Up to 12 months)
- Functional mobility(Up to 12 months)
- Behavior Rating Inventory of Executive Function(Up to 12 months)
- Sensation(Up to 12 months)
- Multiple Sclerosis Functional Composite score(Up to 12 months)
- Berg Balance Scale test(Up to 12 months)
- Muscle strength(Up to 12 months)
- Bone density(Up to 12 months)
- Selective Reminding test(Up to 12 months)
- Equiscale balance test(Up to 12 months)
- Symbol Digit Modalities test(Up to 12 months)
Investigators
Feng Yang, PhD
Assistant Professor
Georgia State University