Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication

Phase 3

Recruiting

• Conditions: Infection Primary
• Interventions: Drug: herbal intracanal medication paste; Drug: Meta paste

• Registration Number: NCT05657132
• Lead Sponsor: Nahda University

Brief Summary

studying the antibacterial effect of Cosuts paste as an intracanal medication against Enterococcus faecalis that present in necrotic primary teeth

Detailed Description

The children were randomly divided into two groups (I, II) Group I (N=12): using Costus-based paste as an intracanal medicament. Group II (N= 12): Calcium hydroxide iodoform paste (Metapex) as an intracanal medicament.

Procedure:

Access opening was started. then a swab was taken from the distal root canal with a dry paper point and transferred to a sterile test tube. The canals were filled with an intracanal medication according to the patient group. In group I, the canals was filled with a previously prepared Costus-based paste for one week, and In Group II, the canals were filled with Meta paste for one week. After 1 week, the paste was washed away from the canals then another swab was taken from the distal canal by a dry paper point as done before preoperatively.

The 2 swabs were transferred within 2 hours to the lab for bacterial culture and detection of enterococcus faecalis count.

Study Timeline

• Study Start: 2021-08-19
• Status Verified: 2022-12
• Primary Completion: 2022-12-10
• Study First Submitted: 2022-12-10
• Study First Submitted QC: 2022-12-10
• Last Update Submitted: 2022-12-10
• Study First Posted: 2022-12-20
• Last Update Posted: 2022-12-20
• Study Completion: 2022-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Patients with clinically and radiologically diagnosed infected primary teeth in their mandibular arch.
• Teeth should be deeply carious, with a history of spontaneous pain and carious exposures with necrotic pulp was also be selected
• radiographic evidence of adequate alveolar bone support, and absence of internal or external resorption.
• tooth must be restorable.

Exclusion Criteria

• vital tooth
• Non restorable teeth

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Costus paste	herbal intracanal medication paste	Costus paste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar
metapaste	Meta paste	metapaste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar

Primary Outcome Measures

Name	Time	Method
Bacterial count	1 weak	Colony forming unit

Trial Locations

Locations (1)

NUB University; 🇪🇬 Cairo, Bani Suif, Egypt