Synbiotic and Antibiotic Associated Diarrhea
- Conditions
- Antibiotic Associated Diarrhea.
- Registration Number
- IRCT20171119037543N2
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Children with 2 months to 14 years age
Children who are admitted in Imam Hosein Hospital in Isfahan City
Children who are candidate for Antibiotic therapies due to infections for equal and more than 5 days
Parent's willingness to participating in this study
Acute or chronic diarrhea before starting Antibiotic
Having Antibiotic therapy during last 2 months
Having prophylactic Antibiotic treatment
Having Clostridium Difficile Associated Diarrhea during last 3 months
Having underlying gastrointestinal disease
Having central vein catheterization
Having history of using probiotics during last 7 days
Having immune deficiency
Having underlying cardiovascular disease
Having sever malnutrition or sever illness
Having long term use of medications with gastrointestinal effects
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of defecation. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Stool Consistency. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Bristol Stool Scale questionnaire.;Incidence of diarrhea. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Diarrhea duration. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.
- Secondary Outcome Measures
Name Time Method Incidence of constipation. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Presence of blood in stool. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.