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临床试验/NCT02689297
NCT02689297已完成4 期

Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

Tokyo Medical and Dental University0 个研究点目标入组 30 人开始时间: 2013年9月最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
30
主要终点
Three different volatile sulfur compounds

研究概览

简要总结

The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

详细描述

Thirty male monk volunteers who matched with the including criteria were divided randomly into two groups. Both groups were practiced to brush their teeth with scrubbing method for one week. Then, each group were instructed to do different additional protocol regimen- group A have to do mouth washing and tooth brushing and group B have to practice tongue cleaning addition to tooth brushing for three weeks. At the fifth week, both groups were instructed to practice tooth brushing, mouth washing and tongue cleaning. Three different volatile sulfur compounds were measured by oral chroma. Tongue characteristics, oral examination were checked as the outcomes of this study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Clinical diagnosis of oral malodor
  • No systemic diseases and no severe dental diseases
  • At least 20 functional teeth

排除标准

  • Risky oral habit (smoking and betel quid chewing)
  • Current use of antibiotics or any drugs
  • Current use of any kind of mouthwash

结局指标

主要结局

Three different volatile sulfur compounds

时间窗: up to 5weeks

Investigator measured three different volatile sulfur compounds: hydrogen sulfide, methyl mercaptan, dimethyl sulfide concentrations (ng/10ml) by using Oral chroma.

次要结局

  • Number of teeth with bleeding on probing(up to 5weeks)
  • Plaque index score(up to 5weeks)
  • Tongue coating characteristics(up to 5weeks)
  • Oral Health examination(up to 5weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ei Ei Aung

Graduate student, Department of Oral Health Promotion

Tokyo Medical and Dental University

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