Are subjective pain scores related to facial muscle activity?

Not Applicable

Completed

• Conditions: Measuring pain felt by patients with a measurement of how their faces move; Signs and Symptoms

• Registration Number: ISRCTN61520151
• Lead Sponsor: Queen Victoria Hospital

Brief Summary

2022 Abstract results in https://www.medrxiv.org/content/10.1101/2022.11.23.22282655v1.full-text International Association for the Study of Pain (IASP) 2022 World Congress on Pain, 19-23 September 2022, Toronto, Canada (added 12/12/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-10
• Study Completion: 2022-01-31
• Last Update Posted: 8 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patient:
1. Adult age 18+ with full capacity
2. ASA I (normal, healthy) and II (mild systemic disease; no functional limitation)
3. Fluent in English

Trauma/procedure:
1. Patients have received superficial trauma to the hand only
2. Patient is due to have examination and operation performed under local anaesthesia only
3. A digital ring block is planned for anaesthesia/analgesia during the procedure
4. No sedation/intravenous opioids are due to be administered
5. Oral analgesia via WHO analgesic ladder is permitted

Exclusion Criteria

1. A history of chronic pain on long term opiates
2. A diagnosis of dementia/long-term memory impairment
3. Previous facial surgery (previous minor facial laceration suturing does not exclude)
4. Cosmetic facial procedures, e.g. botox injection or cosmetic fillers”
5. Past history of facial neuromuscular disease eg Bell’s palsy
6. Pregnant

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. The timing and magnitude of the muscle response from the peri-orbital muscles to the painful stimulus (a local anaesthetic injection to the finger), recorded non-invasively using specialized goggles containing muscle sensors at baseline, during painful stimulus and post stimulus<br>2. Pain measured using a visual analogue scale (VAS) pain score linked into a computer at baseline, during painful stimulus and post stimulus

Secondary Outcome Measures

Name	Time	Method
1. The amplitude of peri-orbital facial muscle activity (Corrugator Supercilii + Orbicularis Oculi), recorded non-invasively using specialized goggles containing muscle sensors at baseline, during painful stimulus and post stimulus<br>2. Heart rate and heart rate variability, measured using sensors in the specialised goggles and using a continuous ECG recording at baseline, during painful stimulus and post stimulus